FlyBase Allele Report: Dmel\EcR[RNAi.UAS.cIa]

General Information

Symbol

Dmel\EcR^RNAi.UAS.cIa

Species

D. melanogaster

Name

FlyBase ID

FBal0244203

Feature type

allele

Associated gene

Dmel\EcR

Associated Insertion(s)

Carried in Construct

P{UAS-EcR.RNAi.I}

Key Links

Transgenic product class

RNAi_reagent

(Ishimoto et al., 2009)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ishimoto et al., 2009)

Mutagen

in vitro construct

(Ishimoto et al., 2009)

Progenitor genotype

Carried in construct

P{UAS-EcR.RNAi.I}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat of a fragment of EcR.

(Ishimoto et al., 2009)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

EcR

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal courtship behavior | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Ishimoto et al., 2009)

abnormal courtship behavior | RU486 conditional, with Scer\GAL4^{Mef2.247.Switch}

(Ishimoto et al., 2009)

abnormal memory | RU486 conditional, with Scer\GAL4^{elav.Switch.PO}

(Ishimoto et al., 2009)

abnormal memory | RU486 conditional, with Scer\GAL4^{Mef2.247.Switch}

(Ishimoto et al., 2009)

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of EcR^{dsRNA.Scer\UAS.cIa} (under the control of RU486-inducible Scer\GAL4^{elav.Switch.PO}) in male flies before and during courtship behaviour training results in defective courtship long-term memory. Induction of EcR^{dsRNA.Scer\UAS.cIa} expression after the courtship training period does not affect courtship long-term memory.

Expression of EcR^{dsRNA.Scer\UAS.cIa} in the mushroom body (under the control of RU486-inducible Scer\GAL4^{Mef2.247.Switch}) before and during courtship behaviour training results in defective courtship long-term memory.

(Ishimoto et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

EcR^RNAi.UAS.cIa

EcR^{dsRNA.Scer\UAS.cIa}

EcR^{dsRNA.UAS.cIa}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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