FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Hr96+tHa
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General Information
Symbol
Dmel\Hr96+tHa
Species
D. melanogaster
Name
FlyBase ID
FBal0260738
Feature type
allele
Associated gene
Dmel\Hr96
Associated Insertion(s)
Carried in Construct
P{Hr96+tHa}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Sieber and Thummel, 2009)
Progenitor genotype
Carried in construct
P{Hr96+tHa}
Cytology
Description

A genomic fragment carrying the Hr96 gene.

(Sieber and Thummel, 2009)
Allele components
Component
Use(s)
Regulatory region(s)
Hr96
Encoded product / tool
Hr96
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Animals bearing two copies of Hr96+tHa, in addition to the endogenous Hr96 locus, die at a slower rate than wild type controls when transferred to starvation media.

      Animals bearing two copies of Hr96+tHa, in addition to the endogenous Hr96 locus, have wild type levels of glycogen under both normal and starved feeding conditions compared to controls.

      Animals bearing two copies of Hr96+tHa, in addition to the endogenous Hr96 locus, have elevated triacylglycerol (TAG) levels in both fed and starved conditions relative to controls.

      Fat body cells of animals bearing two copies of Hr96+tHa, in addition to the endogenous Hr96 locus, are of wild type size but contain enlarged lipid droplets.

      Compared to controls, increased levels of neutral lipids are detected in the midgut epithelium of animals bearing two copies of Hr96+tHa, in addition to the endogenous Hr96 locus.

      (Sieber and Thummel, 2009)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      From M. Horner.

      (Sieber and Thummel, 2009)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Hr96+tHa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)