Amino acid replacement: W1562term.
G21575141A
W1562term | InR-PA; W1562term | InR-PB; W1562term | InR-PC; W1562term | InR-PD
W1562term
G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified). Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
InR574/InR574 somatic clones of terminal tracheal cells are smaller in size, but have a similar nucleus size and branch number to heterozygous controls in third instar larvae. Heterozygous neighboring stalk cells show a mild capacity for compensatory branching leading to a slight increase in the occurrence of two or more adherens junctions between the two cells, compared to one junction in wild-type controls.
InR574/InR574 somatic clones of tracheocytes in the dorsal trunk are also smaller in size and tend to be oval in shape rather than hexagonal, as observed for control wild-type clones.
sprout574 mutant terminal cells are tiny, but the tracheal cells are nevertheless robustly branched.
sprout574 mutant eye cell clones,in an EGUF/hid eye assay (where forced expression of a cell death gene in the eye imaginal disc eliminates wild-type cells, leaving the adult eyes to develop almost entirely from clones of homozygous mutant cells), exhibit a growth defect.