FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\incmw
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General Information
Symbol
Dmel\incmw
Species
D. melanogaster
Name
FlyBase ID
FBal0279993
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Associated Insertion(s)
Cytology
Description

A w+mW.hs marker has been inserted just upstream of the inc stop codon.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutant flies show a reduction in sleep duration compared to controls. Sleep is reduced during both light and dark periods, but the sleep levels of the mutant flies drop in anticipation of light-dark and dark-light conditions, suggesting that the circadian clock is intact. The mutant flies show a reduction in sleep bout length accompanied by an increase in sleep bout number and show an increased latency to sleep after lights-off. The mutant flies show a modest reduction in activity during wakefulness. The mutant flies show reduced sleep homeostasis, lacking a detectable sleep rebound after 12 or 24 hours of sleep deprivation. The mutant flies are more easily woken by a rotational stimulus compared to wild type controls.

A proportion of mutant flies lack either an α- or β-lobe in the mushroom body.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

DATfmn incmw double mutants do not sleep significantly less than either single mutant.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)