FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Trf2SV40
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General Information
Symbol
Dmel\Trf2SV40
Species
D. melanogaster
Name
FlyBase ID
FBal0358524
Feature type
allele
Associated gene
Dmel\Trf2
Associated Insertion(s)
TI{TI}Trf2SV40
Carried in Construct
Key Links
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Osadchiy et al., 2019)
Mutagen
phiC31 integrase
(Osadchiy et al., 2019)
Progenitor genotype
TI{TI}Trf2mCherry.attP
(Osadchiy et al., 2019)
Associated Insertion(s)
TI{TI}Trf2SV40
Cytology
Description

Sequence comprised of 1: a loxP cassette containing a w+* marker and 2: the splice acceptor site of a Trf intron (the intron that is normally upstream of the protein-coding exons) followed by an SV40 polyadenylation signal, has been inserted into the attP site present in TI{TI}Trf2mCherry.attP. This results in a Trf2 locus that can not produce any Trf2 protein. The loxP cassette containing a Disc\RFPmCherry.Act5C marker that was present on the TI{TI}Trf2mCherry.attP chromosome is also still present in the Trf2 intron, upstream of the newly inserted sequence.

(Osadchiy et al., 2019)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Trf2SV40
      trf2sv40
      (Osadchiy et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)