FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\HDAC3HEBI
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General Information
Symbol
Dmel\HDAC3HEBI
Species
D. melanogaster
Name
FlyBase ID
FBal0392819
Feature type
allele
Associated gene
Dmel\HDAC3
Associated Insertion(s)
TI{TI}HDAC3HEBI
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Tang et al., 2023)
Progenitor genotype
TI{TI}HDAC3Δ
(Tang et al., 2023)
Associated Insertion(s)
TI{TI}HDAC3HEBI
Cytology
Description

The attP-flanked w+* marker in TI{TI}HDAC3Δ has been replaced with genomic HDAC3 sequence that extends from 1173bp upstream of the transcription start site to 771bp downstream of the 3'UTR, and which has been mutated to carry a combination of substitutions that abrogates interaction with the Smr protein (mutations are K47E, L60T, R61K, E118A, G119A, Q121V, H125K, N128Q and H129A). The inserted HDAC3 sequence is flanked by inverted attR sites generated during the recombination event.

(Tang et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      HDAC3HEBI
      (Tang et al., 2023)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)