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General Information
Name
SNF2-LIKE CHROMATIN REMODELERS
Species
D. melanogaster
Symbol
SNF2
FlyBase ID
FBgg0001587
Date last reviewed
2020-07-08
Number of members
16
Description
Description
Snf2-like chromatin remodelers are a family of helicase-like proteins that direct energy derived from ATP hydrolysis into the mechanical remodelling of chromatin structure. They are so-called due to the presence of a domain homologous to the helicase-like ATPase domain of the S. cerevisiae Snf2 protein. This domain, the Snf2 domain, consists of two tandem RecA-like folds and contains seven conserved helicase-related sequence motifs that classify it as part of the helicase superfamily 2 (SF2). However, Snf2 proteins are not bona fide helicases, lacking the ability to separate nucleic acid strands. Instead, Snf2 proteins are DNA translocases that apply an ATP-dependent torsional strain to DNA, which provides the necessary force to remodel nucleosomes or in some cases other DNA-protein complexes. (Adapted from PMID:21862382.)
Notes on Group
Source Material
The SNF2-LIKE CHROMATIN REMODELERS Gene Group has been compiled by FlyBase curators using the following publication(s): Schneiderman et al., 2009 .
Key Gene Ontology (GO) terms
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
Members (16)
For all members:
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
Chromodomain-helicase-DNA-binding protein 1
CHD-1, dCHD1, Chromodomain-helicase-DNA-binding protein
Helicase 89B
BTAF1, 89B helicase, Mot1
INO80 complex subunit
dIno80
Imitation SWI
NURF, CHRAC, ACF, dNURF, dISWI
kismet
l(2)k16510, KIS-L, EP474
lodestar
factor 2, Horka, Fs(3)Hor, Negative transcription elongation factor 2
Mi-2
dMi-2, Pha, dMi2, l(3)L1243, l(3)S000606
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
SNF2
SNF2-LIKE CHROMATIN REMODELERS
Secondary FlyBase ID(s)
References (3)