Acetoacetate and 3-hydroxybutanoate are thought to be imported into cells via transporters belonging to the monocarboxylate transporter (MCT) family. So far, only Sln has been shown to be involved in acetoacetate uptake by neurons. The mitochondrial transporters are not known. Acat2 is a paralog of Acat1. As it is predicted to localize in the cytosol and there is no information for its involvement in ketone body metabolism, Acat2 is not included in the list.
| molecular function | biological process | cellular component |
|---|