Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CR using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CR in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
In females there are about 250 tandemly arrayed rRNA genes in each of the two X chromosome. However, when only a single X is present, as in X/O males or X/In(1)sc4Lsc8R females, there are approximately 400 rRNA genes per X. This phenomenon, referred to as 'compensation', results from the disproportionate replication of rDNA in somatic cells of adults and is controlled by the CR locus. CR is novel in that it exhibits both trans- and contiguous-cis-acting properties. It acts in trans to detect the presence of its partner locus in the homologue and if that partner locus is absent, it acts in cis to drive the disproportionate replication of those rRNA genes that are contiguous with it. The observed disproportionate rDNA replication may occur primarily in polytene nuclei. CR is not required for the 'magnification' or 'reduction' of germ line rDNA.