FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Human Disease Model Report: 3-methylglutaconic aciduria
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General Information
Name
3-methylglutaconic aciduria
FlyBase ID
FBhh0000180
Disease Ontology Term
Parent Disease
OMIM
Overview

This report describes general characteristics of the group of diseases classified as 3-methylglutaconic aciduria. 3-methylglutaconic aciduria is a genetically heterogeneous disorder, with multiple implicated genes and mapped loci. A list of 3-methylglutaconic aciduria subtypes, as defined by OMIM, can be found by following the link in the "OMIM phenotypic series" section, below. The table below includes links to more detailed reports for subtypes that have been investigated using fly models.

[updated Jun. 2017 by FlyBase; FBrf0222196]

Disease Summary Information
Parent Disease Summary: 3-methylglutaconic aciduria
OMIM report
Symptoms and phenotype

Methylglutaconic aciduria is a clinically and genetically heterogeneous disorder whose metabolic landmark is urinary excretion of 3-methylglutaconic acid (3-MGA).

(OMIM, 2013-)
Genetics
Cellular phenotype and pathology
Molecular information
External links
Disease synonyms
3-Methylglutaconic aciduria
MGCA
Ortholog Information
Human gene(s) in FlyBase
    Other mammalian ortholog(s) used
      D. melanogaster Gene Information (0)
      Other Genes Used: Viral, Bacterial, Synthetic (0)
        Summary of Physical Interactions (0 groups)
        Alleles Reported to Model Human Disease (Disease Ontology) (0 alleles)
        Alleles Representing Disease-Implicated Variants
        Genetic Tools, Stocks and Reagents
        Sources of Stocks
        Contact lab of origin for a reagent not available from a public stock center.
        Bloomington Stock Center Disease Page
        Related mammalian, viral, bacterial, or synthetic transgenes
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila transgenes
        Allele
        Transgene
        Publicly Available Stocks
        RNAi constructs available
        Allele
        Transgene
        Publicly Available Stocks
        Selected Drosophila classical alleles
        Allele
        Allele class
        Mutagen
        Publicly Available Stocks
        References (2)