FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Rpn7, Rpn6
FlyBase ID
FBig0000091463
Interaction Network
Interactions Browser links
Rpn7 network
Rpn6 network
Reported Interactions
FBrf0217724-1.CH.MW
Reference
Pathare et al., 2012
Description
physical association
Assay
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rpn7 

Rpn7

bait

His tag

Rpn6 

Rpn6

prey
Rpn6 
Rpn6 
Rpn6 
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Rpn6 
interaction domain
sufficient binding region
aa 30-422

coordinates relative to Rpn6-PB

Rpn6 
interaction domain
necessary binding region
aa 391-422

coordinates relative to Rpn6-PB

Rpn6 
interaction domain residues 366,369,370
mutation disrupting interaction
aa 366,369,370

S366K,I369A,L370A, coordinates relative to Rpn6-PB

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey produced as a recombinant fusion protein in bacterial system.

(Pathare et al., 2012)
FBrf0218395-748.DPiM
Reference
Guruharsha et al., 2011
Description
physical association
Assay
Collection
DPiM-2
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Rpn7 
unspecified role
Rpn7 
unspecified role
Rpn7 
unspecified role
Rpn6 
unspecified role
Rpn6 
unspecified role
Rpn6 
unspecified role
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

HGScore = 174.53965

External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (2)