Subject: ADRC-826C
Dear Andrew,
We are currently curating the abstracts for the upcoming Bellevue
(Seattle) Annual Drosophila Research Conference, for FlyBase. I am
writing in connection with your abstract:
'Molecular genetic analysis of dENL/AF9: A gene involved in cell fate
control and disease.'
You mention a gene that is new to FlyBase, ENL/AF9.
Do you have a map location for ENL/AF9? It is nice if we can keep as
many gene records as possible anchored to the map. Were you intending
to stick with ENL/AF9 as the gene symbol and name (we must drop the 'd'
\- we do not prefix with d for Drosophila in FlyBase)? Or perhaps you
have by now discovered that ENL/AF9 corresponds to a previously defined
locus.
Thank you for your help,
with best wishes,
Rachel.
Subject: Re: ADRC-826C
Hi Rachel:
Our 'new' gene, dENL/AF9 is a homolog of two human genes named ENL and AF9.
These names are essentially meaningless out of their context in humans
(they have no relation to function or phenotypes), and we have not yet
assigned a new name until we make more progress on the genetics. We have
roughly mapped the gene to 88E-F, but without more molecular and genetic
details we cannot assign a gene order in that region, so we have been
hesitant to make any such assignments.
I am not sure how you want to treat this information; we have been
reluctant to re-name as we don't want to create any unnecessary confusion
if it turns out to be a known locus. I hope this helps in some way.
Regards,
Andrew Dingwall