Gene or accession: CG4432
Release: 3
Gene annotation error
Gene CG4432 has incorrect exon/intron structure or translation start site.
Gene cDNA sequence:
>PGRP-LC transcript, splice form x
GTCACTCGAACGCGCCGCTGCTCAACGATTCGAAATTGGCGCGAAACGGTATAAAAAGTTCGACTTACAAATTGGCTATA
TAGTATAGACGCTCAAATATCAAACGAGCTGCAACGGTTTTCGTCGGCAATTTAAAATGCTCATGATGTGATGTTTGCCG
AGAGCTGTGCCTAGTCAGCCGTTTTGCCATACGAAAAATAATGTACCGCCCAATCTGCTAAATAGGAAGGCTAACACATA
ACGCTCAGAGATCCAGAGAAAATATCAATCTGGTTACGTGACTGTCACGATAGTTCGACATGCCTTTTAGCAATGAAACG
GAAATGAGCCAATGTTCCAATGCGAAACGTAGAGTAAACGATCCGTTGACTGGACCAAAAAACTGCAGTACTTCGTCCAC
AGACTCGGGCGTTATACTAAACGATAATGTGGCGGCATTCCGGCCGGAGAAGGAGACCAAAGATCGGGGGACGGGCGAAG
GGCAGTTCCAATCGAAATCGGAAGAGAAAACGGAATCCAAGCGTATCAGCGTTGAGCACACTGTCAATATAACAACGGAA
AATGTTGGAAAGACATCTTCGCCGGCGGTTTCCATACGGAGTACCACAATTTCCGTTGTGTCCATCGATGATAATGCCAT
CGACTCGAGTAGTATTGATAGTGATTCGGAGGCCGAAGCGGAGGATTATACGGTCCAGAAGCTGGGTCACCAGGTCACCT
ACCCGCCCAACAGTTCACACCTGCGCGACCTTAACCAGGGTCTAACGGTGATCAGTCGCCATGTGGCGCCAGGTGAGGCG
GCAGTACCACCACCCAATCCCCTGGAAGCTGGCATTGTGGCCAAGCAAATACTGAACGGTAATCTGGCCGTGGCCACGCC
CACATCGCCGGCGGGCGGTGCCACGCAGGGTATTGGCAGCATCGCCCTGACCAACTCCACAGATGTGACGTTCGGTGATA
AGCATTTCTACGAGGGACCCGTGACGATACAACAGTTTCTCATCGATAATCGGGACAAGTGGAAACCGGGCGAGGGACCA
GCTGGTGGACAGGATAACCCCGCATTCAATGGTGGTCCCAGCACGAATGGAAGTGCGCCGGGCTCCAAACACGAAGATCC
GGCGCAAACCCCACCAATTTGTCCTTTTCTGCCCAACACTGTCGGACGCAAGGCCGTCACAGTTACAGTGGTTTTTGTAA
CTTTAACCTTCCTGCTGGGTATCGTACTGGCCACCACCACAAATCTCTTCGGAAAGACGTTGAACCAAACGGACTTGGAT
GTCATCGATAATAGCACATTGGTGATCCTAAAAGTAGCCGAGTGGGGCGGAAGACCTGCCAAGAGGATGTTGGATGCGCA
ACAGTTGCCCATCAATCGGGTGGTCATCTCGCACACCGCCGCTGAGGGTTGCGAATCGAGGGAAGTCTGCTCCGCCCGGG
TGAATGTCGTCCAATCGTTTCACATGGACAGCTGGGGTTGGGACCACATAGGCTACAACTTTCTCGTGGGCGGCGATGGC
CGTGTGTACGAGGGGCGTGGCTGGGACTATGTGGGCGCTCACACCAAGGGTTATAATAGAGGAAGCATTGGTATATCCTT
TATTGGAACCTTCACGACAAGAAAACCCAACGAACGGCAGTTAGAGGCATGCCAACTGCTTTTGCAAGAGGGCGTTCGTC
TTAAGAAATTGACGACGAATTATCGTCTTTATGGCCATCGTCAACTGAGTGCCACGGAGAGTCCCGGGGAGGAGCTCTAC
AAGATCATTAAAAAGTGGCCGCACTGGTCACACGAAATCTAATAAGTCATGTATTATATAAAAATTACAAGTAAATAGAG
TCTTAAGAAATATG
>PGRP-LC transcript, splice form y
GTCACTCGAACGCGCCGCTGCTCAACGATTCGAAATTGGCGCGAAACGGTATAAAAAGTTCGACTTACAAATTGGCTATA
TAGTATAGACGCTCAAATATCAAACGAGCTGCAACGGTTTTCGTCGGCAATTTAAAATGCTCATGATGTGATGTTTGCCG
AGAGCTGTGCCTAGTCAGCCGTTTTGCCATACGAAAAATAATGTACCGCCCAATCTGCTAAATAGGAAGGCTAACACATA
ACGCTCAGAGATCCAGAGAAAATATCAATCTGGTTACGTGACTGTCACGATAGTTCGACATGCCTTTTAGCAATGAAACG
GAAATGAGCCAATGTTCCAATGCGAAACGTAGAGTAAACGATCCGTTGACTGGACCAAAAAACTGCAGTACTTCGTCCAC
AGACTCGGGCGTTATACTAAACGATAATGTGGCGGCATTCCGGCCGGAGAAGGAGACCAAAGATCGGGGGACGGGCGAAG
GGCAGTTCCAATCGAAATCGGAAGAGAAAACGGAATCCAAGCGTATCAGCGTTGAGCACACTGTCAATATAACAACGGAA
AATGTTGGAAAGACATCTTCGCCGGCGGTTTCCATACGGAGTACCACAATTTCCGTTGTGTCCATCGATGATAATGCCAT
CGACTCGAGTAGTATTGATAGTGATTCGGAGGCCGAAGCGGAGGATTATACGGTCCAGAAGCTGGGTCACCAGGTCACCT
ACCCGCCCAACAGTTCACACCTGCGCGACCTTAACCAGGGTCTAACGGTGATCAGTCGCCATGTGGCGCCAGGTGAGGCG
GCAGTACCACCACCCAATCCCCTGGAAGCTGGCATTGTGGCCAAGCAAATACTGAACGGTAATCTGGCCGTGGCCACGCC
CACATCGCCGGCGGGCGGTGCCACGCAGGGTATTGGCAGCATCGCCCTGACCAACTCCACAGATGTGACGTTCGGTGATA
AGCATTTCTACGAGGGACCCGTGACGATACAACAGTTTCTCATCGATAATCGGGACAAGTGGAAACCGGGCGAGGGACCA
GCTGGTGGACAGGATAACCCCGCATTCAATGGTGGTCCCAGCACGAATGGAAGTGCGCCGGGCTCCAAACACGAAGATCC
GGCGCAAACCCCACCAATTTGTCCTTTTCTGCCCAACACTGTCGGACGCAAGGCCGTCACAGTTACAGTGGTTTTTGTAA
CTTTAACCTTCCTGCTGGGTATCGTACTGGCCACCACCACAAATCTCTTCGGAAAGACGTTGAACCAAACGAATGATCCT
AAAATCCATGTGGATGGAAAACTAGTTGTGGTCAGTATAAAAGGCTGGGGTGGTATGCCTACTAGAGGAAACCTAAAGCC
ATTTAAACTTCCGGTCTCCAAGGTAATTATCTCTGAGACTCCACCCGAGATATGTACGACACAGGATTCCTGTTCTTATT
GGACTCGAGTAACCCAAAGCAGGCACATGGATACCTTCAACTGGAGTCAAGTGGGATATAATTTTCTTGTGGGCGGAGAT
GGACGTATTTACGAGGGGCGTGGCTGGAACTACATGGGCGATCATACGAGGGACAATAATAACAACAGTATCGGTATTAC
ATTTTTGGGAACATTTCGACGACAGGAGCCGACGCCAAAATCATTAGAGGCATGTCAGCTGCTCATCGCTCAAGGTGTTC
GCCTCAAGAAACTAAAGCCAGATTACCAACTGCTGGGACATCGGCAAATCACAGGCACTTTGATGCCCGGCGAGGAACTC
TATAGAATCATTCAAACCTGGAATAACTGGTACAATCTGACGAAAACTTGGCCCGATCTGCATATGACTCAATAGTTATA
ATTAATACAATCAAGAACGAATAAAGGTGTTCAAAAAATG
>PGRP-LC transcript, splice form a (corresponds to CG4432-RB)
GTCACTCGAACGCGCCGCTGCTCAACGATTCGAAATTGGCGCGAAACGGTATAAAAAGTTCGACTTACAAATTGGCTATA
TAGTATAGACGCTCAAATATCAAACGAGCTGCAACGGTTTTCGTCGGCAATTTAAAATGCTCATGATGTGATGTTTGCCG
AGAGCTGTGCCTAGTCAGCCGTTTTGCCATACGAAAAATAATGTACCGCCCAATCTGCTAAATAGGAAGGCTAACACATA
ACGCTCAGAGATCCAGAGAAAATATCAATCTGGTTACGTGACTGTCACGATAGTTCGACATGCCTTTTAGCAATGAAACG
GAAATGAGCCAATGTTCCAATGCGAAACGTAGAGTAAACGATCCGTTGACTGGACCAAAAAACTGCAGTACTTCGTCCAC
AGACTCGGGCGTTATACTAAACGATAATGTGGCGGCATTCCGGCCGGAGAAGGAGACCAAAGATCGGGGGACGGGCGAAG
GGCAGTTCCAATCGAAATCGGAAGAGAAAACGGAATCCAAGCGTATCAGCGTTGAGCACACTGTCAATATAACAACGGAA
AATGTTGGAAAGACATCTTCGCCGGCGGTTTCCATACGGAGTACCACAATTTCCGTTGTGTCCATCGATGATAATGCCAT
CGACTCGAGTAGTATTGATAGTGATTCGGAGGCCGAAGCGGAGGATTATACGGTCCAGAAGCTGGGTCACCAGGTCACCT
ACCCGCCCAACAGTTCACACCTGCGCGACCTTAACCAGGGTCTAACGGTGATCAGTCGCCATGTGGCGCCAGGTGAGGCG
GCAGTACCACCACCCAATCCCCTGGAAGCTGGCATTGTGGCCAAGCAAATACTGAACGGTAATCTGGCCGTGGCCACGCC
CACATCGCCGGCGGGCGGTGCCACGCAGGGTATTGGCAGCATCGCCCTGACCAACTCCACAGATGTGACGTTCGGTGATA
AGCATTTCTACGAGGGACCCGTGACGATACAACAGTTTCTCATCGATAATCGGGACAAGTGGAAACCGGGCGAGGGACCA
GCTGGTGGACAGGATAACCCCGCATTCAATGGTGGTCCCAGCACGAATGGAAGTGCGCCGGGCTCCAAACACGAAGATCC
GGCGCAAACCCCACCAATTTGTCCTTTTCTGCCCAACACTGTCGGACGCAAGGCCGTCACAGTTACAGTGGTTTTTGTAA
CTTTAACCTTCCTGCTGGGTATCGTACTGGCCACCACCACAAATCTCTTCGGAAAGACGTTGAACCAAAGTAAGATCAGA
GATGACGACGATTACAGACAAAATATTCCAATCAATTCAACAATAGATCTGGACAACATTGGTGGTGGACTAATACTGAG
ATTCGTGGAGCGTCAGCAATGGCTCGCACAGCCGCCACAGAAGGAGATTCCCGATCTGGAGCTGCCCGTGGGATTGGTCA
TAGCCTTGCCCACCAATTCAGAAAATTGCAGCACACAGGCGATCTGTGTGCTCCGAGTTCGTCTGCTGCAGACCTACGAT
ATAGAATCGTCGCAGAAGTGTGATATTGCGTACAACTTTCTGATTGGCGGAGATGGAAATGTATATGTGGGACGGGGCTG
GAATAAAATGGGTGCCCACATGAACAATATAAACTATGACTCGCAGAGTCTTAGCTTCGCCTATATCGGATCGTTTAAGA
CCATCCAGCCGTCGGCCAAGCAACTAAGTGTTACTCGTCTTTTGCTGGAGCGTGGCGTAAAGCTGGGCAAGATTGCACCA
AGCTACCGATTTACGGCGAGCAGTAAATTGATGCCAAGTGTAACCGATTTTAAGGCGGATGCGCTCTACGCAAGCTTCGC
CAACTGGACTCATTGGTCGTGAATAGGTTAAGAGCTATTTCGATATTTTGCAATACTATCATTTATTTTCGTATTGATTT
TGTATCATAGGTGTTCTCCCATTAATGTGTGGCATATTCGATTTAGCTAGAGTAACGATTCGTTTAAAAAGAAAATGTGA
TATTAAATAAAACAAAATGATTT
Protein sequence:
>PGRP-LC transcript, splice form x
MPFSNETEMSQCSNAKRRVNDPLTGPKNCSTSSTDSGVILNDNVAAFRPEKETKDRGTGEGQFQSKSEEKTESKRISVEH
TVNITTENVGKTSSPAVSIRSTTISVVSIDDNAIDSSSIDSDSEAEAEDYTVQKLGHQVTYPPNSSHLRDLNQGLTVISR
HVAPGEAAVPPPNPLEAGIVAKQILNGNLAVATPTSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFLIDNRDK
WKPGEGPAGGQDNPAFNGGPSTNGSAPGSKHEDPAQTPPICPFLPNTVGRKAVTVTVVFVTLTFLLGIVLATTTNLFGKT
LNQTDLDVIDNSTLVILKVAEWGGRPAKRMLDAQQLPINRVVISHTAAEGCESREVCSARVNVVQSFHMDSWGWDHIGYN
FLVGGDGRVYEGRGWDYVGAHTKGYNRGSIGISFIGTFTTRKPNERQLEACQLLLQEGVRLKKLTTNYRLYGHRQLSATE
SPGEELYKIIKKWPHWSHEI
>PGRP-LC transcript, splice form y
MPFSNETEMSQCSNAKRRVNDPLTGPKNCSTSSTDSGVILNDNVAAFRPEKETKDRGTGEGQFQSKSEEKTESKRISVEH
TVNITTENVGKTSSPAVSIRSTTISVVSIDDNAIDSSSIDSDSEAEAEDYTVQKLGHQVTYPPNSSHLRDLNQGLTVISR
HVAPGEAAVPPPNPLEAGIVAKQILNGNLAVATPTSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFLIDNRDK
WKPGEGPAGGQDNPAFNGGPSTNGSAPGSKHEDPAQTPPICPFLPNTVGRKAVTVTVVFVTLTFLLGIVLATTTNLFGKT
LNQTNDPKIHVDGKLVVVSIKGWGGMPTRGNLKPFKLPVSKVIISETPPEICTTQDSCSYWTRVTQSRHMDTFNWSQVGY
NFLVGGDGRIYEGRGWNYMGDHTRDNNNNSIGITFLGTFRRQEPTPKSLEACQLLIAQGVRLKKLKPDYQLLGHRQITGT
LMPGEELYRIIQTWNNWYNLTKTWPDLHMTQ
>PGRP-LC transcript, splice form a (corresponds to CG4432-RB)
MPFSNETEMSQCSNAKRRVNDPLTGPKNCSTSSTDSGVILNDNVAAFRPEKETKDRGTGEGQFQSKSEEKTESKRISVEH
TVNITTENVGKTSSPAVSIRSTTISVVSIDDNAIDSSSIDSDSEAEAEDYTVQKLGHQVTYPPNSSHLRDLNQGLTVISR
HVAPGEAAVPPPNPLEAGIVAKQILNGNLAVATPTSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFLIDNRDK
WKPGEGPAGGQDNPAFNGGPSTNGSAPGSKHEDPAQTPPICPFLPNTVGRKAVTVTVVFVTLTFLLGIVLATTTNLFGKT
LNQSKIRDDDDYRQNIPINSTIDLDNIGGGLILRFVERQQWLAQPPQKEIPDLELPVGLVIALPTNSENCSTQAICVLRV
RLLQTYDIESSQKCDIAYNFLIGGDGNVYVGRGWNKMGAHMNNINYDSQSLSFAYIGSFKTIQPSAKQLSVTRLLLERGV
KLGKIAPSYRFTASSKLMPSVTDFKADALYASFANWTHWS
Comments: We have sequenced cDNA corresponding to the PGRP-LC gene (CG4432)
transcripts. We find three major splice forms:
LCx (first described by Choe et al. 2002, accession AF500096)
LCy (Werner et al. 2003, JBC in press, accession numbers not yet assigned)
LCa (first described by Werner et al. 2000, accession AF207539). This
transcript corresponds to CG4432-RB. We believe that the CG4432-RA isoform
does not exist.