Abstract
During development, mechanical forces sculpt tissues into myriad forms. Actomyosin contractility generated within the cell has an increasingly appreciated role in this process, but how tissue forces relate to the physical properties of the extracellular matrix is still poorly understood, particularly at longer time scales and the whole tissue level. A new paper in Development addresses these issues using Drosophila leg development as a model, taking advantage of an ex vivo culturing method. We caught up with first author Amsha Proag and last author Magali Suzanne, group leader at the Centre for Integrative Biology in Toulouse, France, to hear more about the story.
