FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term G2/M transition of mitotic cell cycle ID (Ontology) GO:0000086 (Gene Ontology)
Definition The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
Also Known As "mitotic G2/M transition"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      13
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 Genes
 G2/M transition of mitotic cell cycle (all annotations which use CV term, excluding "NOT" statements)      13
     acts_upstream_of_positive_effect | G2/M transition of mitotic cell cycle       1
     involved_in | G2/M transition of mitotic cell cycle      12
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cell cycle phase transition
 |__mitotic cell cycle phase transition__
 |__cell cycle G2/M phase transition_____|
mitotic cell cycle process               |
 |__mitotic cell cycle phase transition__|
                                         G2/M transition of mitotic cell cycle  46 rec.
                                          |__regulation of G2/M transition of mitotic cell cycle 37 rec.
                                              |__negative regulation of G2/M transition of mitotic cell cycle(+) 27 rec.
                                              |__positive regulation of G2/M transition of mitotic cell cycle(+) 4 rec.
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Is a mitotic cell cycle phase transition
cell cycle G2/M phase transition
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Synonyms
  • "mitotic G2/M transition" EXACT
Secondary IDs
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Reactome:R-HSA-69275 "G2/M Transition"