FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

G2/M transition of mitotic cell cycle

ID (Ontology)

GO:0000086 (Gene Ontology)

Definition

The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.

Also Known As

"mitotic G2/M transition"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
G2/M transition of mitotic cell cycle (all annotations which use CV term, excluding "NOT" statements)
acts_upstream_of_positive_effect \| G2/M transition of mitotic cell cycle
involved_in \| G2/M transition of mitotic cell cycle

Spanning Tree (Parents/Children)

cell cycle phase transition
 |__mitotic cell cycle phase transition__
 |__cell cycle G2/M phase transition_____|
mitotic cell cycle process               |
 |__mitotic cell cycle phase transition__|
                                         G2/M transition of mitotic cell cycle  44 rec.
                                          |__regulation of G2/M transition of mitotic cell cycle 35 rec.
                                              |__negative regulation of G2/M transition of mitotic cell cycle(+) 25 rec.
                                              |__positive regulation of G2/M transition of mitotic cell cycle(+) 4 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	mitotic cell cycle phase transition cell cycle G2/M phase transition
Part of
Synonyms & Secondary IDs
Synonyms
	"mitotic G2/M transition" EXACT
Secondary IDs

External Crossreferences & Linkouts
	Reactome:R-HSA-69275 "G2/M Transition"