FB2026_03 , released September 17, 2026

CV Term Report

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General Information

Term

RNA polymerase II promoter clearance

ID (Ontology)

GO:0001111 (Gene Ontology)

Definition

A process that mediates the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.[ PubMed:15020047 PubMed:22982364 PubMed:31628251 ]

Also Known As

"promoter clearance from RNA polymerase II promoter" ; "promoter escape from RNA polymerase II promoter" ; "promoter-paused RNA polymerase II release"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
RNA polymerase II promoter clearance (all annotations which use CV term, excluding "NOT" statements)
involved_in \| RNA polymerase II promoter clearance

Spanning Tree (Parents/Children)

DNA-templated transcription
 |__promoter clearance during DNA-templated transcription__
 |__transcription by RNA polymerase II_____________________|
RNA biosynthetic process                                   |
 |__promoter clearance during DNA-templated transcription__|
                                                           RNA polymerase II promoter clearance  7 rec.
                                                            |__regulation of promoter clearance from RNA polymerase II promoter
                                                                |__negative regulation of promoter clearance from RNA polymerase II promoter
                                                                |__positive regulation of promoter clearance from RNA polymerase II promoter

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	promoter clearance during DNA-templated transcription
Part of	transcription by RNA polymerase II
Synonyms & Secondary IDs
Synonyms
	"promoter clearance from RNA polymerase II promoter" EXACT "promoter escape from RNA polymerase II promoter" EXACT "promoter-paused RNA polymerase II release" EXACT
Secondary IDs

External Crossreferences & Linkouts