FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

transcription coactivator activity

ID (Ontology)

GO:0003713 (Gene Ontology)

Definition

A transcription coregulator activity that activates or increases the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coactivators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators. A fourth class of coactivator activity is the bridging of a DNA-binding transcription factor to the general (basal) transcription machinery. The Mediator complex, which bridges sequence-specific DNA binding transcription factors and RNA polymerase, is also a transcription coactivator.[ PubMed:10213677 PubMed:16858867 ]

Also Known As

"transcription co-activator activity"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

Choose a record type to view annotations for this term and its child terms. Direct annotations and full annotation statements below also provide HitList buttons.

Results list data from multiple species. Choose a record type above to open its HitList.

Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS
Genes (FBgn)	GO_CELLULAR_COMPONENT
Genes (FBgn)	GO_MOLECULAR_FUNCTION

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Gene Groups	Genes
transcription coactivator activity (all annotations which use CV term, excluding "NOT" statements)
contributes_to \| transcription coactivator activity	--
enables \| transcription coactivator activity	--

Spanning Tree (Parents/Children)

  transcription regulator activity
   |__transcription coregulator activity
       |__transcription coactivator activity  94 rec.

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	transcription coregulator activity
Part of
Synonyms & Secondary IDs
Synonyms
	"RNA polymerase II transcription co-activator activity" RELATED "RNA polymerase II transcription coactivator activity" RELATED "RNA polymerase II transcription mediator activity" RELATED "transcription co-activator activity" EXACT
Secondary IDs

External Crossreferences & Linkouts