FB2026_02 , released June 18, 2026

CV Term Report

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General Information

Term

protein K63-linked ubiquitination

ID (Ontology)

GO:0070534 (Gene Ontology)

Definition

A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.[ PubMed:15556404 ]

Also Known As

"protein K63-linked polyubiquitination"

Comment

Links to External Ontologies

QuickGO data AmiGO data

Annotations

Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)

Data Class	Field	Direct annotations
Genes (FBgn)	GO_BIOLOGICAL_PROCESS

Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records

Full annotation statements	Relevant FlyBase reports
Full annotation statements	Genes
protein K63-linked ubiquitination (all annotations which use CV term, excluding "NOT" statements)
involved_in \| protein K63-linked ubiquitination

Spanning Tree (Parents/Children)

  protein ubiquitination
   |__protein polyubiquitination
       |__protein K63-linked ubiquitination  7 rec.
           |__regulation of protein K63-linked ubiquitination
               |__negative regulation of protein K63-linked ubiquitination
               |__positive regulation of protein K63-linked ubiquitination

Spanning Tree View Settings
Parents/Children View Depth	Show hierarchy levels: for parents, for children
Relationships
Is a	protein polyubiquitination
Part of
Synonyms & Secondary IDs
Synonyms
	"protein K63-linked polyubiquitination" EXACT
Secondary IDs

External Crossreferences & Linkouts