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General Information
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| Term |
ATAC complex |
ID (Ontology) |
GO:0140672 (Gene Ontology) |
| Definition |
A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation.[ PubMed:19936620 PubMed:20562830 PubMed:28966424 ] |
| Also Known As |
"Ada two A containing complex" ; "Ada Two-A containing complex" ; "Ada-Two-A-containing complex" (for all, see Synonyms field below) |
| Comment |
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Links to External Ontologies
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QuickGO data AmiGO data
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Annotations
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Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
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| Data Class | Field | Records |
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| Genes (FBgn) | GO_CELLULAR_COMPONENT | 13 |
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Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
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| Full annotation statements | Relevant FlyBase reports |
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| Gene Groups | Genes |
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ATAC complex (all annotations which use CV term, excluding "NOT" statements) | 1 | 13 | part_of | ATAC complex | -- | 13 |
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Relationships
