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| Term | ATAC complex | ID (Ontology) | GO:0140672 (Gene Ontology) | |||||||||||
| Definition | A chromatin remodeling complex that regulates transcription via acetylation primarily of nucleosomal histones H3 and possibly H4. Shares the histone acetylation (HAT) module of GCN5/PCAF-ADA2-ADA3-SGF29 (or orthologs) with the related SAGA complex (GO:0000124). Contains HAT subunits GCN5 or PCAF in a mutually exclusive manner. In addition to the HAT module contains DR1/NC2B, KAT14, MBIP, WDR5, YEATS2 and ZZZ3 or orthologs. Also regulates the activity of non-histone targets and orchestrates mitotic progression by regulating Cyclin A degradation through acetylation.[ PubMed:19936620 PubMed:20562830 PubMed:28966424 ] | |||||||||||||
| Also Known As | "Ada two A containing complex" ; "Ada Two-A containing complex" ; "Ada-Two-A-containing complex" (for all, see Synonyms field below) | |||||||||||||
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histone acetyltransferase complex |__SAGA-type complex |__ATAC complex 14 rec. |
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| Is a | SAGA-type complex | ||
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