FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
CV Term Report
Help Close All Open All
General Information
Term facultative heterochromatin formation ID (Ontology) GO:0140718 (Gene Ontology)
Definition The compaction of chromatin into a conformation that is refractory to transcription but that can be converted to euchromatin and allow transcription in specific contexts. These can be temporal (e.g., developmental states or specific cell-cycle stages), spatial (e.g., nuclear localization changes from the center to the periphery or vice versa due to exogenous factors/signals), or parental/heritable (e.g., monoallelic gene expression). In metazoa, this involves the methylation of histone H3K27, and in certain cases methylation of H3K9. On the other hand, in unicellular eukaryotes, only methylation of H3K9 is involved and H3K27 is not methylated.[ PubMed:17936700 ]
Also Known As "facultative heterochromatin assembly" ; "fHC assembly"
Comment
Links to External Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
    Results list data from multiple species. Click on a button above and use the 'Filter by species' options on the resulting HitList to retrieve species-specific data.
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       6
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 facultative heterochromatin formation (all annotations which use CV term, excluding "NOT" statements)       6
     involved_in | facultative heterochromatin formation       6
Spanning Tree (Parents/Children)
Only view relationship: 
cellular component assembly_________________________
negative regulation of gene expression, epigenetic__|
heterochromatin organization________________________|
                                                    heterochromatin formation
                                                     |__facultative heterochromatin formation  8 rec.
                                                         |__rDNA heterochromatin formation 2 rec.
                                                         |   |__regulation of rDNA heterochromatin formation(+)
                                                         |__siRNA-independent facultative heterochromatin formation
                                                         |   |__regulation of siRNA-independent facultative heterochromatin formation
                                                         |__siRNA-mediated facultative heterochromatin formation
                                                             |__regulation of siRNA-mediated facultative heterochromatin formation
Spanning Tree View Settings
Parents/Children
View Depth
Show hierarchy levels: for parents, for children
hide Relationships
Is a heterochromatin formation
Part of
hide Synonyms & Secondary IDs
Synonyms
  • "facultative heterochromatin assembly" EXACT
    "fHC assembly" EXACT
Secondary IDs
hide External Crossreferences & Linkouts