FB2025_01 , released February 20, 2025
Allele: Dmel\vgunspecified
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General Information
Symbol
Dmel\vgunspecified
Species
D. melanogaster
Name
FlyBase ID
FBal0046663
Feature type
allele
Associated gene
Dmel\vg
Associated Insertion(s)
Carried in Construct
Also Known As
unspecified
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Mature homozygous adult flies have a significantly lower body glycogen content than mature wild-type flies.

        (Barnes, 1994)

        There is a decrease in the apical cell region of the wing discs in homozygous larvae.

        (Ryerse and Nagel, 1984)

        Flies show notum duplications, due to a homeotic transformation of wing base structures to notum.

        (Mglinetz and Balakireva, 1982)

        vgW/vgunspecified flies completely lack wings and halteres and the scutellum is deformed. The postscutellar bristles are usually absent. Development is slow, and only 20-30% of flies eclose. Viability and fertility is reduced.

        (Shukla, 1980)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Other
        Statement
        Reference

        M(3)801, vg[+]/vgunspecified has visible | dominant | heat sensitive phenotype

        (Sinclair et al., 1984)

        Ybbts1, vgunspecified has visible | dominant phenotype

        (Sinclair et al., 1984)

        su(f)8, vgunspecified has visible | dominant | heat sensitive phenotype

        (Sinclair et al., 1984)

        Ybbts1, vg[+]/vgunspecified has visible phenotype

        (Sinclair et al., 1984)

        su(f)8, vg[+]/vgunspecified has visible | heat sensitive phenotype

        (Sinclair et al., 1984)

        M(3)80[+]/M(3)801, vgunspecified has visible | dominant | heat sensitive phenotype

        (Sinclair et al., 1984)
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        vgunspecified; M(3)801 heterozygotes are normal at 22oC. At 29oC they have nicks in the apical part of the wing. su(f)8/Y ; vgunspecified/+ flies are normal at 22oC. At 28oC they have nicked wings and show a bb-like phenotype, having small bristles, slow development and cuticular defects. Ybbts1; vgunspecified/+ flies have nicked wings at 22oC.

        (Sinclair et al., 1984)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        uex1 does not interact with the vgunspecified mutation.

        (Maeda, 1997)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        unspecified
        (Ryerse and Nagel, 1984, Mglinetz and Balakireva, 1982)
        vgunspecified
        Name Synonyms
        Secondary FlyBase IDs
          References (7)