FB2025_01 , released February 20, 2025
Allele: Dmel\Arpc2KG04658
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General Information
Symbol
Dmel\Arpc2KG04658
Species
D. melanogaster
Name
FlyBase ID
FBal0134419
Feature type
allele
Associated gene
Dmel\Arpc2
Associated Insertion(s)
P{SUPor-P}Arpc2KG04658
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{SUPor-P}Arpc2KG04658
Cytology
Description
Allele components
Component
Use(s)
Inserted element
P{SUPor-P}
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  autosomal recessive intellectual developmental disorder
      modeled by Nab2EP3716
      (Rounds et al., 2022)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Somatic mosaic Arc-p34KG04658 eyes exhibit a rough phenotype, with ommatidia displaying a reduced number of photoreceptor cells. In addition, many cells have widened or split rhabdomeres as a result of a lack of retinal elongation.

      (Pham et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Arpc2KG04658/Arpc2[+] is a suppressor | partially of visible | adult stage phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Rounds et al., 2022)

      Arpc2KG04658/Arpc2[+] is a suppressor of abnormal eye color phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Rounds et al., 2022)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Arpc2KG04658/Arpc2[+] is a suppressor | partially of eye phenotype of Nab2EP3716, Scer\GAL4GMR.PU

      (Rounds et al., 2022)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Arc-p34KG04658
      (Pham et al., 2008)
      Arpc2KG04658
      (Rounds et al., 2022)
      arpc2KG04658
      (Chaudhari et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)