FB2025_01 , released February 20, 2025
Allele: Dmel\park+tR
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General Information
Symbol
Dmel\park+tR
Species
D. melanogaster
Name
FlyBase ID
FBal0158834
Feature type
allele
Associated gene
Dmel\park
Associated Insertion(s)
Carried in Construct
P{park+tR}
Also Known As
dpkR
Key Links
Transgenic product class
genomic_DNA
(Pesah et al., 2004)
wild_type
(Pesah et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Pesah et al., 2004)
wild_type
(Pesah et al., 2004)
Mutagen
in vitro construct
(Pesah et al., 2004)
Progenitor genotype
Carried in construct
P{park+tR}
Cytology
Description

Genomic fragment, chromosome 3L, 21098849-21124696, which corresponds to park plus 10-12 kb flanking sequence on either side.

(Pesah et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
park
Encoded product / tool
park
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      park+tR rescues parkP21

      (Ottone et al., 2011)

      park+tR rescues parkP23

      (Ottone et al., 2011)
      Partially rescues

      park+tR partially rescues parkΔ21

      (Pesah et al., 2004)
      Comments

      The reduced body size/mass, reduced lifespan and increased sensitivity to cold an paraquat seen in parkΔ21 homozygous adults are all partially rescued by park+tR. Reduced jump response, flightlessness and indirect flight muscle degeneration in parkΔ21 homozygotes are completely rescued by park+tR.

      (Pesah et al., 2004)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      park+t.R
      park+tR
      Name Synonyms
      Secondary FlyBase IDs
        References (3)