Allele Dmel\unc-5^unspecified

General Information
Symbol	Dmel\unc-5^unspecified	Species	D. melanogaster
Name		FlyBase ID	FBal0191959
Feature type	allele	Associated gene	Dmel\unc-5

Allele class
Mutagen
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Nature of the Allele
Allele class
Mutagen
Mutations Mapped to the Genome

Type Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Cytology
Phenotypic Data
Phenotypic Class
	neuroanatomy defective (Labrador et al., 2005)
Phenotype Manifest In
	abdominal segmental nerve (Labrador et al., 2005) intersegmental nerve (Labrador et al., 2005)
Detailed Description
	Statement Reference In unc-5^unspecified mutants, the dorsally projecting ISN inappropriately crosses the segment boundary and the SNa sometimes stalls or is missing one of the two major branches. However, ISNb guidance is normal. (Labrador et al., 2005)
External Data
Linkouts
Interactions
Phenotypic Class
NOT Suppressor of
Statement Reference unc-5^unspecified is a non-suppressor of neuroanatomy defective \| embryonic stage phenotype of Scer\GAL4^elav.PLu, fra^{ΔC.Scer\UAS.T:Ivir\HA1}, fra^unspecified (Garbe et al., 2007)
Phenotype Manifest In
NOT Suppressor of
Statement Reference unc-5^unspecified is a non-suppressor of ventral nerve cord commissure \| embryonic stage phenotype of Scer\GAL4^elav.PLu, fra^{ΔC.Scer\UAS.T:Ivir\HA1}, fra^unspecified (Garbe et al., 2007)
Additional Comments
Genetic Interactions
Statement Reference Expression of fra[ΔC.Scer\UAS.T:Ivir\HA] driven by Scer\GAL4[elav.PLu] still causes a commissureless phenotype in a fra[unspecified] unc-5[unspecified] double mutant background. (Garbe et al., 2007)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

External Crossreferences & Linkouts
Other Crossreferences

Linkouts

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	unc-5^unspecified
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Garbe et al., 2007, Development 134(24): 4325--4334 Cytoplasmic domain requirements for Frazzled-mediated attractive axon turning at the Drosophila midline. [FBrf0200520] Labrador et al., 2005, Curr. Biol. 15(15): 1413--1419 The homeobox transcription factor even-skipped regulates netrin-receptor expression to control dorsal motor-axon projections in Drosophila. [FBrf0187314]

Allele Dmel\unc-5unspecified

Allele Dmel\unc-5^unspecified