FB2025_01 , released February 20, 2025
Allele: Dmel\αTub84BUbi-p63E.GFP(S65C)
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General Information
Symbol
Dmel\αTub84BUbi-p63E.GFP(S65C)
Species
D. melanogaster
Name
FlyBase ID
FBal0219749
Feature type
allele
Associated gene
Dmel\αTub84B
Associated Insertion(s)
Carried in Construct
P{Ubi-p63E-GFP-α-Tub84B}
Also Known As
GFP-α-tubulin, GFP-TUB, Ubi-GFP-α-tubulin
Key Links
Transgenic product class
wild_type
(Rebollo et al., 2004)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rebollo et al., 2004)
Mutagen
in vitro construct
(Rebollo et al., 2004)
Progenitor genotype
Carried in construct
P{Ubi-p63E-GFP-α-Tub84B}
Cytology
Description

A Ubi-p63E promoter drives expression of a αTub84B-GFP(S65C) fusion protein.

(Rebollo et al., 2004)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
αTub84B
Tagged with
GFP(S65C)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of αTub84BUbi-p63E.T:Avic\GFP-S65C does not cause any obvious changes to brain neuroblast number in third instar larvae compared to wild-type.

      (Zhang et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The increased number of brain neuroblast as well as the asymmetric protein segregation defects (observed both during metaphase and telophase) characteristic for Pfdn2Δ10;pinsP89 double mutants are partially rescued by expression of αTub84BUbi-p63E.T:Avic\GFP-S65C in the double mutant background.

      (Zhang et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      αTub84BUbi-p63E.GFP(S65C)
      αTub84BUbi-p63E.T:Avic\GFP-S65C
      Name Synonyms
      Secondary FlyBase IDs
        References (16)