FB2025_01 , released February 20, 2025
Allele: Dmel\moiR2.Tub
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General Information
Symbol
Dmel\moiR2.Tub
Species
D. melanogaster
Name
FlyBase ID
FBal0221231
Feature type
allele
Associated gene
Dmel\moi
Associated Insertion(s)
Carried in Construct
P{tub-moi-tatl.R2}
Key Links
Transgenic product class
wild_type
(Raffa et al., 2009)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Raffa et al., 2009)
Mutagen
in vitro construct
(Raffa et al., 2009)
Progenitor genotype
Carried in construct
P{tub-moi-tatl.R2}
Cytology
Description

A tubulin promoter drives expression of a fragment encoding the wild-type moi open reading frame and a mutated tatl open reading frame (these genes are encoded by a dicistronic locus).

(Raffa et al., 2009)
Allele components
Component
Use(s)
Encoded product / tool
moi
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      moiR2.Tub rescues moi1/Df(3R)P14

      (Raffa et al., 2009)

      moiR2.Tub rescues moi1/moiS096713

      (Raffa et al., 2009)

      moiR2.Tub rescues moiCB02140/moi1

      (Raffa et al., 2009)

      moiR2.Tub rescues moiM12

      (Raffa et al., 2009)
      Comments

      The telomere fusion defects and lethality of moi1/Df(3R)P14, moi1/moiS096713, moi1/moiCB02140 and moiM12/moiM12 animals are rescued by moiR2.Tub.

      The telomere fusion defects of moiS096713/moiS096713 and moiCB02140/moiCB02140 animals are rescued by moiR2.Tub.

      (Raffa et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      moiR2.Tub
      Name Synonyms
      Secondary FlyBase IDs
        References (2)