UASt regulatory sequences drive expression of an inverted repeat.
The expression of Rpn2KK102356 under the control of Scer\GAL4rn-GAL4-5 induces extensive apoptosis in the imaginal disc.
Fat body cell clones expressing Rpn2KK102356 under the control of Scer\GAL4Act.PU are small in size compared to controls.
Fat bodies dissected from well-fed larvae expressing Rpn2KK102356 under the control of Scer\GAL4Cg.PA contain large cytoplasmic protein aggregates that are never surrounded by membranes. Double-membrane autophagosomes and degrading autolysosomes are also readily detected in well-fed larval samples.