FlyBase Allele Report: Dmel\br[JF02585]

General Information

Symbol

Dmel\br^JF02585

Species

D. melanogaster

Name

FlyBase ID

FBal0239285

Feature type

allele

Associated gene

Dmel\br

Associated Insertion(s)

Carried in Construct

P{TRiP.JF02585}

Also Known As

UAS-br RNAi

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.8.10)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Perkins et al., 2009.8.10)

Mutagen

in vitro construct

(Perkins et al., 2009.8.10)

Progenitor genotype

Carried in construct

P{TRiP.JF02585}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat.

(Perkins et al., 2009.8.10)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-JF02585

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | P-stage, with Scer\GAL4^NP5130

(Zhang et al., 2024)

abnormal neuroanatomy, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

Phenotype Manifest In

enteroendocrine cell | P-stage | increased number, with Scer\GAL4^NP5130

(Zhang et al., 2024)

larval dorsal multidendritic neuron ddaC, with Scer\GAL4^ppk.1.9

(Iyer et al., 2013)

Detailed Description

Statement

Reference

Expression of br^JF02585 in the fat body under the control of Scer\GAL4^DcG results in significant hyperglycaemia.

(Ugrankar et al., 2015)

Expression of br^JF02585 in C-IV neurons under the control of Scer\GAL4^ppk.1.9 results in a reduction in total dendritic length in ddaC neurons. The total number of dendritic branches is also reduced in ddaC neurons.

(Iyer et al., 2013)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

br^JF02585, Scer\GAL4^NP5130 is a suppressor of abnormal cell number | P-stage phenotype of EcR^{B1-ΔC655.F645A.UAS}, Scer\GAL4^NP5130

(Zhang et al., 2024)

br^JF02585/Scer\GAL4^NP5130 is a suppressor of abnormal cell number | P-stage phenotype of Scer\GAL4^NP5130, usp^HMS01620

(Zhang et al., 2024)

br^JF02585, Scer\GAL4^NP5130 is a suppressor of abnormal cell number | P-stage phenotype of Oatp74D^RNAi.UAS.cUa, Scer\GAL4^NP5130

(Zhang et al., 2024)

br^JF02585, Scer\GAL4^NP5130 is a suppressor of abnormal cell number | P-stage phenotype of Eip93F^HMC04773, Scer\GAL4^NP5130

(Zhang et al., 2024)

Phenotype Manifest In

Suppressor of

Statement

Reference

br^JF02585, Scer\GAL4^NP5130 is a suppressor of enteroendocrine cell | P-stage | decreased number phenotype of EcR^{B1-ΔC655.F645A.UAS}, Scer\GAL4^NP5130

(Zhang et al., 2024)

br^JF02585/Scer\GAL4^NP5130 is a suppressor of enteroendocrine cell | P-stage | decreased number phenotype of Scer\GAL4^NP5130, usp^HMS01620

(Zhang et al., 2024)

br^JF02585, Scer\GAL4^NP5130 is a suppressor of enteroendocrine cell | P-stage | decreased number phenotype of Oatp74D^RNAi.UAS.cUa, Scer\GAL4^NP5130

(Zhang et al., 2024)

br^JF02585, Scer\GAL4^NP5130 is a suppressor of enteroendocrine cell | P-stage | decreased number phenotype of Eip93F^HMC04773, Scer\GAL4^NP5130

(Zhang et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

27272

y¹ v¹; P{TRiP.JF02585}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

br^JF02585

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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