FlyBase Allele Report: Dmel\Vml[EY21650]

General Information

Symbol

Dmel\Vml^EY21650

Species

D. melanogaster

Name

FlyBase ID

FBal0240566

Feature type

allele

Associated gene

Dmel\Vml

Associated Insertion(s)

P{EPgy2}Vml^EY21650

Carried in Construct

Also Known As

Vml^EPgy2

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{EPgy2}Vml^EY21650

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EPgy2}

misexpression element

Regulatory region(s)

UASp

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

X:2,276,302..2,276,302 [+]

(Wu et al., 2010, Zhang et al., 2009)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygous embryos produce embryos that hatch.

(Zhang et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhancer of

Statement

Reference

Vml^EY21650/Vml^EY21650 is an enhancer | maternal effect of embryonic/first instar larval cuticle | maternal effect phenotype of pip⁷/pip²

(Zhang et al., 2009)

Vml^EY21650/Vml[+] is an enhancer | maternal effect of embryonic/first instar larval cuticle | maternal effect phenotype of pip⁷/pip²

(Zhang et al., 2009)

Df(2L)Exel7024, Vml^EY21650, Vml[+], + is an enhancer | maternal effect of embryonic/first instar larval cuticle | maternal effect phenotype of pip⁷/pip²

(Zhang et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

The severity of the dorsalisation phenotype seen in embryos derived from pip²/pip⁷ females is increased if the females are also carrying Vml^EY21650/Vml^EY21650, such that 89.5% of the embryos derived from the double mutant females are completely dorsalised.

The severity of the dorsalisation phenotype seen in embryos derived from pip²/pip⁷ females is increased if the females are also carrying Vml^EY21650/+; 48.0% of embryos derived from the double mutant females are completely dorsalised, and only 1.2% are weakly dorsalised.

The severity of the dorsalisation phenotype seen in embryos derived from pip²/pip⁷ females is increased if the females are also carrying Df(2L)Exel7024/+ and Vml^EY21650/+; 69.5% of embryos derived from the double mutant females are completely dorsalised, and none are only weakly dorsalised.

(Zhang et al., 2009)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

24095

y¹ P{EPgy2}Vml^EY21650 w^67c23

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Vml^EPgy2

(Zhang et al., 2009)

Vml^EY21650

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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