FB2025_01 , released February 20, 2025
Allele: Dmel\Ptp4EUAS.GFP
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General Information
Symbol
Dmel\Ptp4EUAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0241991
Feature type
allele
Associated gene
Dmel\Ptp4E
Associated Insertion(s)
Carried in Construct
P{UAS-Ptp4E.GFP}
Also Known As
UAS-Ptp4E-GFP
Key Links
Transgenic product class
wild_type
(Jeon et al., 2008)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Jeon et al., 2008)
Mutagen
in vitro construct
(Jeon et al., 2008)
Progenitor genotype
Carried in construct
P{UAS-Ptp4E.GFP}
Cytology
Description

UAS regulatory sequences drive expression of the long isoform of Ptp4E with a C-terminal GFP fusion.

(Jeon et al., 2008)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ptp4E
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      There is a subtle overexpression phenotype produced by driving Ptp4EScer\UAS.T:Avic\GFP driven by Scer\GAL4elav.PLu in neurons, in which the longitudinal bundles have a "wavy" appearance.

      (Jeon et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      Expression of Ptp4EScer\UAS.T:Avic\GFP under the control of Scer\GAL4btl.PS completely rescues the tracheal defects of Ptp4E1 Ptp10D1 double mutant embryos.

      (Jeon and Zinn, 2009)

      Scer\GAL4btl.PS-driven Ptp4EScer\UAS.T:Avic\GFP-expression is capable of rescuing the lethality and tracheal phenotypes associated with the Ptp4E1-Ptp10D1 double mutant genotypes. Similarly to ubiquitous overexpression of Ptp4EScer\UAS.T:Avic\GFP driven by Scer\GAL4αTub84B.PL, pan-neural overexpression of Ptp4EScer\UAS.T:Avic\GFP driven by Scer\GAL4elav.PLu does not rescue the lethality in a Ptp4E1-Ptp10D1 background.

      (Jeon et al., 2008)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ptp4EScer\UAS.T:Avic\GFP
      Ptp4EUAS.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (3)