FB2025_01 , released February 20, 2025
Allele: Dmel\GαqQ203L.UAS.cPa
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General Information
Symbol
Dmel\GαqQ203L.UAS.cPa
Species
D. melanogaster
Name
FlyBase ID
FBal0260592
Feature type
allele
Associated gene
Dmel\Gαq
Associated Insertion(s)
Carried in Construct
P{UAS-Gαq.Q203L.P}
Key Links
Transgenic product class
missense_variant
(Pinal and Pichaud, 2011)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Pinal and Pichaud, 2011)
Mutagen
in vitro construct
(Pinal and Pichaud, 2011)
Progenitor genotype
Carried in construct
P{UAS-Gαq.Q203L.P}
Cytology
Description

UAS regulatory sequences drive expression of a constitutively active form of Gαq (containing the Q203L amino acid replacement).

(Pinal and Pichaud, 2011)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Gαq
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4unspecified/GαqQ203L.UAS.cPa is a non-suppressor of rhabdomere phenotype of ninaE17

      (Pinal and Pichaud, 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Gα49BQ203L.Scer\UAS.cPa under the control of Scer\GAL4unspecified does not rescue the rhabdomere morphogenesis defects of ninaE17 flies.

      (Pinal and Pichaud, 2011)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Gα49BQ203L.Scer\UAS.cPa
      GαqQ203L.Scer\UAS.cPa
      GαqQ203L.UAS.cPa
      GαqQ203L
      (Pinal and Pichaud, 2011)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)