FB2025_01 , released February 20, 2025
Allele: Dmel\DCP2del21
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General Information
Symbol
Dmel\DCP2del21
Species
D. melanogaster
Name
FlyBase ID
FBal0263542
Feature type
allele
Associated gene
Dmel\DCP2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Lee et al., 2020, Lin et al., 2008)
Mutagen
P-element activity
(Lee et al., 2020)
Progenitor genotype
P{GT1}DCP2BG01766
(Lee et al., 2020)
Cytology
Description

6315bp deletion that removes the entire coding sequence (CDS) of the DCP2-RA isoform. The deletion extends from 652bp upstream to 1528bp downstream of the DCP2-RA CDS.

(Chou, 2020.7.9)

6.3kb deletion that remove the entire coding sequence of DCP2. Generated by imprecise excision of the progenitor P{GT1}DCP2BG01766 insertion.

(Lee et al., 2020)

A 6315 bp deletion covering the entire Dcp2 coding region.

(Lin et al., 2008)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3L:15,819,917..15,826,231 [-]
Comment:

A 6315bp deletion resulting from the imprecise excision of P{GT1}DCP2BG01766 that removes 652 bps upstream and 1528 bps downstream of the DCP2-RA CDS.

(Chou, 2020.7.9)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The average size of P bodies (detected using Dcp1 antibody) in nurse cell cytoplasm in ovaries from Dcp2de21 germline clones is increased ~6 times compared to that of controls.

      (Lin et al., 2008)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      DCP2del21 has increased mortality during development phenotype, suppressible by dbo+t13.7

      (Lee et al., 2020)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      DCP2de21
      DCP2del21
      (Chou, 2020.7.9)
      Dcp2de21
      dDcp2de21
      (Lin et al., 2008)
      dDcp2del21
      (Lee et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)