FlyBase Allele Report: Dmel\Tak1[UAS.cUa]

General Information

Symbol

Dmel\Tak1^UAS.cUa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0284405

Feature type

allele

Associated gene

Dmel\Tak1

Associated Insertion(s)

Carried in Construct

P{UAS-Tak1.U}

Key Links

Transgenic product class

wild_type

(Jones et al., 2008)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Jones et al., 2008)

Mutagen

in vitro construct

(Jones et al., 2008)

Progenitor genotype

Carried in construct

P{UAS-Tak1.U}

Cytology

Description

UAS regulatory sequences drive expression of Tak1.

(Jones et al., 2008)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Tak1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by Alk^UAS.cLa

(Wolfstetter et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal size, with Scer\GAL4^GMR.PF

(Jones et al., 2008)

visible, with Scer\GAL4^GMR.PF

(Jones et al., 2008)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Jones et al., 2008)

Detailed Description

Statement

Reference

Expression of Tak1^Scer\UAS.cUa under the control of Scer\GAL4^GMR.PF results in a strong small eye phenotype.

(Jones et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, Tak1^UAS.cUa has visible phenotype, suppressible | partially by Styp\AvrA^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Scer\GAL4^GMR.PF, Tak1^UAS.cUa has abnormal size phenotype, suppressible | partially by Styp\AvrA^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Jones et al., 2008)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, Tak1^UAS.cUa has visible phenotype, non-suppressible by Styp\AvrA^{m.UAS.Tag:MYC}/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Scer\GAL4^GMR.PF, Tak1^UAS.cUa has abnormal size phenotype, non-suppressible by Styp\AvrA^{m.UAS.Tag:MYC}/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, Tak1^UAS.cUa has eye phenotype, suppressible | partially by Styp\AvrA^UAS.Tag:MYC/Scer\GAL4^GMR.PF

(Jones et al., 2008)

NOT suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, Tak1^UAS.cUa has eye phenotype, non-suppressible by Styp\AvrA^{m.UAS.Tag:MYC}/Scer\GAL4^GMR.PF

(Jones et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Expression of Styp\AvrA^{Scer\UAS.T:Hsap\MYC} almost completely suppresses the small eye phenotype seen when Tak1^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF.

Expression of Styp\AvrA^{m.Scer\UAS.T:Hsap\MYC} does not suppress the small eye phenotype seen when Tak1^Scer\UAS.cUa is expressed under the control of Scer\GAL4^GMR.PF.

(Jones et al., 2008)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Tak1^Scer\UAS.cUa

Tak1^UAS.cUa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (2)

Report Sections

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