FB2025_01 , released February 20, 2025
Allele: Dmel\mdlcΔCCCH.UAS.Tag:HA
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General Information
Symbol
Dmel\mdlcΔCCCH.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0290444
Feature type
allele
Associated gene
Dmel\mdlc
Associated Insertion(s)
Carried in Construct
PBac{UAS-mdlc.ΔCCCH}
Key Links
Transgenic product class
inframe_deletion
(Carney et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Carney et al., 2013)
Mutagen
in vitro construct
(Carney et al., 2013)
Progenitor genotype
Carried in construct
PBac{UAS-mdlc.ΔCCCH}
Cytology
Description

UASt regulatory sequences drive expression of mdlc lacking the CCCH domain. The protein is tagged at the N-terminal end with Tag:HA.

(Carney et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
mdlc
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Neuroblast clones expressing mdlcΔCCCH.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4tub.PU are wild type in size.

      (Carney et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      Scer\GAL4Tub.PU/mdlcΔCCCH.UAS.Tag:HA fails to rescue mdlcc04701

      (Carney et al., 2013)

      Scer\GAL4Tub.PU/mdlcΔCCCH.UAS.Tag:HA fails to rescue mdlcc04701/Df(3R)ED6027

      (Carney et al., 2013)
      Comments

      Expression of mdlcΔCCCH.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4tub.PU fails to rescue mdlcc04701/Df(3R)ED6027 animals to viability.

      Expression of mdlcΔCCCH.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4tub.PU fails to rescue the reduction in size of homozygous mdlcc04701 neuroblast clones.

      (Carney et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      MdlcΔCCCH
      (Carney et al., 2013)
      mdlcΔCCCH.Scer\UAS.T:Ivir\HA1
      mdlcΔCCCH.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)