FlyBase Allele Report: Dmel\pdm3[HMJ21205]

General Information

Symbol

Dmel\pdm3^HMJ21205

Species

D. melanogaster

Name

FlyBase ID

FBal0293023

Feature type

allele

Associated gene

Dmel\pdm3

Associated Insertion(s)

Carried in Construct

P{TRiP.HMJ21205}

Also Known As

P(TRiP.HMJ21205)

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMJ21205}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMJ21205

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^elav.PLu

(Qian et al., 2018)

Phenotype Manifest In

abdominal 4 ventral multidendritic neuron v'td1 | third instar larval stage, with Scer\GAL4^elav.PLu

(Qian et al., 2018)

abdominal 5 ventral multidendritic neuron v'td1 | third instar larval stage, with Scer\GAL4^elav.PLu

(Qian et al., 2018)

abdominal 6 ventral multidendritic neuron v'td1 | third instar larval stage, with Scer\GAL4^elav.PLu

(Qian et al., 2018)

Detailed Description

Statement

Reference

In third instar larvae expressing pdm3^HMJ21205 under the control of Scer\GAL4^elav.PLu a significant proportion of axons from vtd1 neurons of abdominal segments 4-6 contact the midline and collapse in the subesophageal ganglion (SEG). Their initial projections along the lateral tract, followed by a dorsomedial turn in the metathoracic segment and an anterior extension parallel to the midline towards the SEG are similar to wild-type controls. The length of the ventral nerve cord is similar to wild-type controls.

(Qian et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions