FB2025_01 , released February 20, 2025
Allele: Dmel\conuR402A.UAS.Tag:Myr(Unk),Tag:FLAG
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General Information
Symbol
Dmel\conuR402A.UAS.Tag:Myr(Unk),Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0295009
Feature type
allele
Associated gene
Dmel\conu
Associated Insertion(s)
Carried in Construct
P{UAS-conu.R402A.myr.Flag}
Key Links
Transgenic product class
missense_variant
(Neisch et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Neisch et al., 2013)
Mutagen
in vitro construct
(Neisch et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-conu.R402A.myr.Flag}
Cytology
Description

UAS regulates expression of the LD04957 conu cDNA containing a R402A substitution in the arginine finger, with a Tag:Myr(Unk) sequence directly after the start codon, followed by a 3x N-terminal Tag:FLAG tag.

(Neisch et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
conu
Tagged with
Tag:FLAG
Tag:Myr(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\GAL4ap-md544-mediated expression of conuR402A.Scer\UAS.T:Uuuu\Myr5,T:Zzzz\FLAG has no effect on the wing disc epithelium.

      Scer\GAL4GMR.PF-mediated expression of conuScer\UAS.T:Uuuu\Myr5,T:Zzzz\FLAG results in a slightly rough eye.

      (Neisch et al., 2013)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of conuR402A.Scer\UAS.T:Uuuu\Myr5,T:Zzzz\FLAG does not suppress the rough eye of Scer\GAL4GMR.PF Rho1Scer\UAS.cMa flies.

      Scer\GAL4GMR.PF-mediated expression of conuR402A.Scer\UAS.T:Uuuu\Myr5,T:Zzzz\FLAG mildly enhances the rough eye of Rac1GMR.PN flies.

      (Neisch et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      conuR402A.Scer\UAS.T:Uuuu\Myr-Unk,T:Zzzz\FLAG
      conuR402A.Scer\UAS.T:Uuuu\Myr5,T:Zzzz\FLAG
      conuR402A.UAS.Tag:Myr(Unk),Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)