FB2025_01 , released February 20, 2025
Allele: Dmel\nudE11R2
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General Information
Symbol
Dmel\nudE11R2
Species
D. melanogaster
Name
FlyBase ID
FBal0296207
Feature type
allele
Associated gene
Dmel\nudE
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hayashi et al., 2014)
Progenitor genotype
Cytology
Description

Amino acid replacement: Q33term.

(Hayashi et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:9,900,169..9,900,169 [+]
Nucleotide change:

C9900169T

Reported nucleotide change:

C?T

Amino acid change:

Q33term | nudE-PA; Q33term | nudE-PB; Q33term | nudE-PC; Q33term | nudE-PD; Q33term | nudE-PF

Reported amino acid change:

Q33term

(Hayashi et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous germline clones result in a oocyte mis-specification, with most egg chambers containing 16 nurse cells.

      (Hayashi et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      nudE[+]/nudE11R2 is a suppressor | partially of abnormal neuroanatomy phenotype of Scer\GAL4eve.RN2, dar1UAS.Tag:V5,Tag:polyHis

      (Wang et al., 2015)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The supernumerary dendrite phenotype seen in animals expressing dar1Scer\UAS.cYa under the control of Scer\GAL4eve.RN2 (in unipolar motor neurons) or Scer\GAL4P2.4.Pdf (in adult unipolar PDF neurons) is greatly reduced in nudE11R2/+ mutants.

      (Wang et al., 2015)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      11R2
      (Hayashi et al., 2014)
      nudE11R2
      (Wang et al., 2015)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)