FlyBase Allele Report: Dmel\gek[HMS04488]

General Information

Symbol

Dmel\gek^HMS04488

Species

D. melanogaster

Name

FlyBase ID

FBal0300815

Feature type

allele

Associated gene

Dmel\gek

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS04488}

Also Known As

HMS04488

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMS04488}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS04488

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female semi-sterile, with Scer\GAL4^{VP16.mat.αTub67C}

(Sopko et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Females heterozygous for gek^HMS04488 and Scer\GAL4^{mat.αTub67C.T:Hsim\VP16} crossed to gek^HMS04488 males results in: 81% hatching; non-maternal effect.

(Sopko et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

gek^HMS04488/Scer\GAL4^Mz19 is an enhancer of abnormal neuroanatomy | adult stage phenotype of Scer\GAL4^Mz19, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

NOT Enhancer of

Statement

Reference

Hsap\RELA^AD.VT028327/gek^HMS04488, Scer\GAL4^DBD.R22E04 is a non-enhancer of abnormal neuroanatomy | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

NOT Suppressor of

Statement

Reference

Hsap\RELA^AD.VT028327/gek^HMS04488, Scer\GAL4^DBD.R22E04 is a non-suppressor of abnormal neuroanatomy | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Phenotype Manifest In

Enhancer of

Statement

Reference

gek^HMS04488/Scer\GAL4^Mz19 is an enhancer of adult antennal lobe phenotype of Scer\GAL4^Mz19, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

gek^HMS04488/Scer\GAL4^Mz19 is an enhancer of neuron projection | adult stage phenotype of Scer\GAL4^Mz19, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

NOT Enhancer of

Statement

Reference

Hsap\RELA^AD.VT028327/gek^HMS04488, Scer\GAL4^DBD.R22E04 is a non-enhancer of adult antennal lobe phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Hsap\RELA^AD.VT028327/gek^HMS04488, Scer\GAL4^DBD.R22E04 is a non-enhancer of neuron projection | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

NOT Suppressor of

Statement

Reference

Hsap\RELA^AD.VT028327/gek^HMS04488, Scer\GAL4^DBD.R22E04 is a non-suppressor of adult antennal lobe phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Hsap\RELA^AD.VT028327/gek^HMS04488, Scer\GAL4^DBD.R22E04 is a non-suppressor of neuron projection | adult stage phenotype of Hsap\RELA^AD.VT028327, Scer\GAL4^DBD.R22E04, Ten-m^UAS.Tag:V5

(Xu et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

57379

y¹ sc^* v¹ sev²¹; P{TRiP.HMS04488}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

gek^HMS04488

Name Synonyms

Secondary FlyBase IDs

References (4)

Report Sections

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