FB2025_01 , released February 20, 2025
Allele: Dmel\elavUAS.Tag:HA.cZa
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General Information
Symbol
Dmel\elavUAS.Tag:HA.cZa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Zaharieva
FlyBase ID
FBal0318101
Feature type
allele
Associated gene
Dmel\elav
Associated Insertion(s)
Carried in Construct
PBac{UAS-HA.elav}
Key Links
Transgenic product class
wild_type
(Zaharieva et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zaharieva et al., 2015)
Mutagen
in vitro construct
(Zaharieva et al., 2015)
Progenitor genotype
Carried in construct
PBac{UAS-HA.elav}
Cytology
Description

UASt regulatory sequences drive expression of elav tagged at the N-terminal end with Tag:HA.

(Zaharieva et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
elav
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of elavScer\UAS.T:Ivir\HA1.cZa under the control of Scer\GAL4dsx.PU yields pharate adults that show no genital differentiation in both sexes and impaired development of male sex combs. Male pigmentation is unaffected and flies look otherwise normal.

      (Zaharieva et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      elavUAS.Tag:HA.cZa/Scer\GAL4elav.PZ rescues elav5

      (Zaharieva et al., 2015)
      Comments

      Expression of elavScer\UAS.T:Ivir\HA1.cZa under the control of Scer\GAL4elav.PZ rescues the small eye phenotype seen in elav5 mutant eyes (generated by expressing elavelav.PZ and excising the FRT cassette in the eye primordium).

      (Zaharieva et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      elavScer\UAS.T:Ivir\HA1.cZa
      elavUAS.Tag:HA.cZa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Zaharieva
      Secondary FlyBase IDs
        References (1)