FB2025_01 , released February 20, 2025
Allele: Dmel\Wee1UASp.Venus
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General Information
Symbol
Dmel\Wee1UASp.Venus
Species
D. melanogaster
Name
FlyBase ID
FBal0321369
Feature type
allele
Associated gene
Dmel\Wee1
Associated Insertion(s)
Carried in Construct
P{UASp-Wee1.VFP}
Key Links
Transgenic product class
wild_type
(Varadarajan et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Varadarajan et al., 2016)
Mutagen
in vitro construct
(Varadarajan et al., 2016)
Progenitor genotype
Carried in construct
P{UASp-Wee1.VFP}
Cytology
Description

UASp regulatory sequences drive expression of Wee1 tagged with Venus.

(Varadarajan et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
Wee1
Tagged with
Venus
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Wee1UASp.Venus/Scer\GAL4VP16.bam is a suppressor of male sterile | recessive phenotype of Myt11

      (Varadarajan et al., 2016)
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Wee1UASp.Venus/Scer\GAL4VP16.bam is a non-suppressor of fusome | male | adult stage phenotype of Myt11

      (Varadarajan et al., 2016)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Wee1Scer\UAS.P\T.T:Avic\GFP-YFP.Venus under the control of Scer\GAL4bam.T:Hsim\VP16 almost completely rescues the centriole engagement and meiotic spindle abnormalities as well as the male sterility of Myt11 homozygous mutant adults but does not restore the fusome defects.

      (Varadarajan et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Wee1Scer\UAS.P\T.T:Avic\GFP-YFP.Venus
      Wee1UASp.Venus
      Name Synonyms
      Secondary FlyBase IDs
        References (2)