FB2025_01 , released February 20, 2025
Allele: Dmel\Cpsf100UAS.A
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General Information
Symbol
Dmel\Cpsf100UAS.A
Species
D. melanogaster
Name
FlyBase ID
FBal0327321
Feature type
allele
Associated gene
Dmel\Cpsf100
Associated Insertion(s)
Carried in Construct
M{UAS-Cpsf100.A}
Key Links
Transgenic product class
cDNA
(Shan et al., 2017)
wild_type
(Shan et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Shan et al., 2017)
wild_type
(Shan et al., 2017)
Mutagen
in vitro construct
(Shan et al., 2017)
Progenitor genotype
Carried in construct
M{UAS-Cpsf100.A}
Cytology
Description

UAS regulatory sequences drive expression of isoform A of Cpsf100 (cloned from DGRC FMO13689).

(Shan et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Cpsf100
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      Scer\GAL4VP16.bam/Cpsf100UAS.A is an enhancer of neoplasia | adult stage | male phenotype of tut4

      (Shan et al., 2017)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Scer\GAL4VP16.bam/Cpsf100UAS.A is an enhancer of testis phenotype of tut4

      (Shan et al., 2017)

      Scer\GAL4VP16.bam/Cpsf100UAS.A is an enhancer of spermatogonium phenotype of tut4

      (Shan et al., 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The moderate spermatogonial tumor phenotype (with large tumors, >1/6 of overall testis length, being very rare) observed in testes of tut4 homozygous mutant males is weakly enhanced by Scer\GAL4bam.T:Hsim\VP16-driven expression of Cpsf100Scer\UAS.A in the mutant background but the proportion of large tumors remains <10%.

      (Shan et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cpsf100Scer\UAS.A
      Cpsf100UAS.A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)