FlyBase Allele Report: Hsap\ETFRF1[UAS.cFa]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Hsap\ETFRF1^UAS.cFa

General Information

Symbol

Hsap\ETFRF1^UAS.cFa

Species

H. sapiens

Name

UAS construct a of Fernandez-Acosta

FlyBase ID

FBal0385596

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

PBac{UAS-hETFRF1.F}

Key Links

Transgenic product class

(Fernandez-Acosta et al., 2022)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Fernandez-Acosta et al., 2022)

Mutagen

in vitro construct

(Fernandez-Acosta et al., 2022)

Progenitor genotype

Carried in construct

PBac{UAS-hETFRF1.F}

Cytology

Description

UASt regulates expression of a Drosophila codon-optimized version of Hsap\ETFRF1.

(Fernandez-Acosta et al., 2022)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\ETFRF1^UAS.cFa, Scer\GAL4^Act5C.PI is a suppressor of decreased cell size | larval stage phenotype of Scer\GAL4^Act5C.PI, osi^GD15140

(Fernandez-Acosta et al., 2022)

Hsap\ETFRF1^UAS.cFa, Scer\GAL4^ppl.PP is a suppressor | partially of increased mortality during development phenotype of Scer\GAL4^ppl.PP, osi^GD15140

(Fernandez-Acosta et al., 2022)

Hsap\ETFRF1^UAS.cFa, Scer\GAL4^ppl.PP is a suppressor of decreased rate of feeding behavior | larval stage phenotype of Scer\GAL4^ppl.PP, osi^GD15140

(Fernandez-Acosta et al., 2022)

Hsap\ETFRF1^UAS.cFa, Scer\GAL4^ppl.PP is a suppressor of abnormal behavior | larval stage phenotype of Scer\GAL4^ppl.PP, osi^GD15140

(Fernandez-Acosta et al., 2022)

Hsap\ETFRF1^UAS.cFa, Scer\GAL4^Cg.PU is a suppressor | partially of increased mortality during development phenotype of Scer\GAL4^Cg.PU, osi^GD15140

(Fernandez-Acosta et al., 2022)

Phenotype Manifest In

Suppressor of

Statement

Reference

Hsap\ETFRF1^UAS.cFa, Scer\GAL4^Act5C.PI is a suppressor of larval fat cell phenotype of Scer\GAL4^Act5C.PI, osi^GD15140

(Fernandez-Acosta et al., 2022)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\ETFRF1^UAS.cFa

Name Synonyms

UAS construct a of Fernandez-Acosta

Secondary FlyBase IDs

References (1)

Report Sections