FlyBase Allele Report: Dmel\sals[ΔProR.UAS.Tag:FLAG]

General Information

Symbol

Dmel\sals^{ΔProR.UAS.Tag:FLAG}

Species

D. melanogaster

Name

FlyBase ID

FBal0399142

Feature type

allele

Associated gene

Dmel\sals

Associated Insertion(s)

Carried in Construct

P{UAS-sals.ΔProR.FLAG}

Key Links

Transgenic product class

inframe_deletion

(Farkas et al., 2024)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

inframe_deletion

(Farkas et al., 2024)

Mutagen

in vitro construct

(Farkas et al., 2024)

Progenitor genotype

Carried in construct

P{UAS-sals.ΔProR.FLAG}

Cytology

Description

UASt regulatory sequences drive expression of sals cDNA with the proline-rich motif deleted; tagged at the N-terminal with 3xTag:FLAG.

(Farkas et al., 2024)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

sals

Tagged with

Tag:FLAG

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal flight, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

abnormal flight, with Scer\GAL4^Mef2.PU, sals^f07849

(Farkas et al., 2024)

abnormal size | adult stage, with Scer\GAL4^Mef2.PU, sals^f07849

(Farkas et al., 2024)

abnormal size | P-stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

flightless, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

flightless, with Scer\GAL4^Mef2.PU, sals^f07849

(Farkas et al., 2024)

increased size | adult stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

some die during P-stage, with Scer\GAL4^Mef2.PU, sals^f07849

(Farkas et al., 2024)

Phenotype Manifest In

filamentous actin | adult stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

indirect flight muscle | adult stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

indirect flight muscle | adult stage, with Scer\GAL4^Mef2.PU, sals^f07849

(Farkas et al., 2024)

indirect flight muscle | P-stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

sarcomere | adult stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

sarcomere | adult stage, with Scer\GAL4^Mef2.PU, sals^f07849

(Farkas et al., 2024)

sarcomere | P-stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

Z disc | adult stage, with Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^Mef2.PU, sals^{ΔProR.UAS.Tag:FLAG} has increased size | adult stage phenotype, suppressible | partially by DAAM^RNAi.UAS.FH2, Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

Other

Statement

Reference

Fhos^KK108388, Scer\GAL4^Mef2.PU, sals^{ΔProR.UAS.Tag:FLAG} has abnormal size | adult stage phenotype

(Farkas et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^Mef2.PU, sals^{ΔProR.UAS.Tag:FLAG} has indirect flight muscle | adult stage phenotype, suppressible | partially by DAAM^RNAi.UAS.FH2, Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

Scer\GAL4^Mef2.PU, sals^{ΔProR.UAS.Tag:FLAG} has sarcomere | adult stage phenotype, suppressible | partially by DAAM^RNAi.UAS.FH2, Scer\GAL4^Mef2.PU

(Farkas et al., 2024)

Other

Statement

Reference

Fhos^KK108388, Scer\GAL4^Mef2.PU, sals^{ΔProR.UAS.Tag:FLAG} has sarcomere | adult stage phenotype

(Farkas et al., 2024)

Fhos^KK108388, Scer\GAL4^Mef2.PU, sals^{ΔProR.UAS.Tag:FLAG} has indirect flight muscle | adult stage phenotype

(Farkas et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

sals^{ΔProR.UAS.Tag:FLAG}/Scer\GAL4^Mef2.PU rescues sals^f07849

(Farkas et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

sals^{ΔProR.UAS.Tag:FLAG}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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