FB2025_01 , released February 20, 2025
Gene Group: RAB GTPASE ACTIVATING PROTEINS
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General Information
Name
RAB GTPASE ACTIVATING PROTEINS
Species
D. melanogaster
Symbol
RABGAP
FlyBase ID
FBgg0000331
Date last reviewed
2015-08-06
Number of members
25
Description
Description
RabGAPs are GTPase activating proteins for Rab family GTPases. RabGAPs share a common TBC (Tre-2/Bub2/Cdc16) domain. (Adapted from PMID:15731001 and FBrf0158741).
Notes on Group

In mammalian systems, Rab3-GAP is composed of two subunits, catalytic and non-catalytic (PMID:9733780). CG31935 and Rab3-GAP encode the orthologous subunits, respectively. Rab3-GAP, being a regulatory subunit, is not included in this list.

Source Material
The RAB GTPASE ACTIVATING PROTEINS Gene Group has been compiled using the following publication(s): Gabernet-Castello et al., 2013, Laflamme et al., 2012, and Bernards, 2003 .
Key Gene Ontology (GO) terms
Molecular Function
GTPase activator activity
Biological Process
Cellular Component
Related Gene Groups
Parent group(s)
RAS SUPERFAMILY GTPASE ACTIVATING PROTEINS
Other related group(s)
RAB GTPASES
RAB GUANINE NUCLEOTIDE EXCHANGE FACTORS
Members (25)
For all members:
GO ribbon stack
 molecular functionbiological processcellular component
Gene Symbol
Gene Name
Also Known As
Source Material for Membership
CG1695
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG4041
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG5916
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG7742
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG8155
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG12241
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG16896
(Gabernet-Castello et al., 2013, Laflamme et al., 2012)
CG17883
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
CG42795
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
Evi5
Ecotropic viral integration site 5
MRE21
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
GAPcenA
GTPase activating protein and centrosome-associated
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
GAPsec
GTPase activating protein, SECIS-dependent read-through
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
plx
pollux
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
Rab3GAP1
RAB3 GTPase activating protein subunit 1
(Bernards, 2003)
RN-tre
Related to the N terminus of tre oncogene
tre oncogene-related protein
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
sky
skywalker
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
tbc
trabuco
(Gabernet-Castello et al., 2013, Laflamme et al., 2012)
TBC1D5
TBC1 domain family member 5
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
TBC1d7
TBC1 domain family member 7
dTBC1D7
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
Tbc1d8-9
TBC1 domain family member 8/9
Tbc1d8b
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
Tbc1d15-17
TBC1 domain family member 15/17
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
TBC1D16
TBC1 domain family member 16
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
Tbc1d22
TBC1 domain family member 22
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
TBC1D23
TBC1 domain family member 23
tbc1
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
wkd
whacked
(Gabernet-Castello et al., 2013, Laflamme et al., 2012, Bernards, 2003)
External Data
Equivalent Group(s)
Other resource(s)
Synonyms and Secondary IDs
Synonym(s)
RABGAP
RAB GTPASE ACTIVATING PROTEINS
Rab-GAP
Secondary FlyBase ID(s)
References (4)