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General Information
Interaction Type
Interacting Genes
FlyBase ID
FBig0000098790
Interaction Network
Interactions Browser links
AGO2 network
mir-ban network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0179363-5.coIP.NB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO2 
AGO2
bait
TAP tag
ban
prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.
AGO2 associates only with the mature form of ban miRNA, not the pre-miRNA.
Mature ban miRNA coimmunoprecipitates with AGO1, AGO2 and Fmr1 in this assay. By contrast, the ban pre-miRNA coimmunoprecipitates only with AGO1.
FBrf0191204-6.coIP.NB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO2 
AGO2
bait
HA tag
bantam
prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
ban (mature miRNA and pre-miRNA) coimmunoprecipitates with AGO1, and to a lesser extent, with AGO2 as well.
Source was cell extract of S2 cell line; bait produced from transfected construct; prey produced from endogenous gene.
FBrf0221629-2.FB.A
Reference
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO2 
DmAgo2
bait
MBP tag
AGO2 
bantam
prey
[32]P label
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
AGO2 
C-terminal domain
sufficient binding region
aa 816-1214
coordinates relative to AGO2-PB
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Interaction in vitro; bait produced as a recombinant fusion protein in bacterial system; prey chemically synthesized and labeled in vitro.
FBrf0224072-3.coIP.NB
Description
physical association
Collection
Source/Stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
AGO2 
AGO2
bait
FLAG tag
ban
prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction
Source was cell extract of S2 cell line; bait produced from tagged transgenic construct; prey produced from endogenous gene.
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (4)