Dmel\P{GawB}c584 Insertion

General Information
Symbol	Dmel\P{GawB}c584	Species	D. melanogaster
Name		FlyBase ID	FBti0004500
Feature type	transposable_element_insertion_site
Description
Inserted element	P{GawB}	Expression data	GAL4 reporter/driver
Affected gene(s)	Scer\GAL4	Viability / fertility
Causes allele(s)	Scer\GAL4^c584	Stock availability	1 publicly available
LINE ID
Genomic Location
Chromosomal location	2	Sequence location
Member of Large Scale Dataset(s)
Dataset
Recent Updates
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FB2013_03
FB2013_02
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Detailed Mapping Data
Chromosome (arm)	2 (Cook, 2010.7.28)
Sequence Location
Orientation
Cytological location (computed by FlyBase)
Cytological location (reported)
Comments concerning location
Sequence Data
Flanking sequence
Inserted Element
Construct	P{GawB}
Location-dependent role	GAL4 driver/enhancer trap (Brand and Perrimon, 1993)
Size	11.279Kb
Associated alleles	Scer\GAL4^wB w^+mW.hs
Molecular map
Affected Gene(s)
Insertion may affect gene	Scer\GAL4 (Manseau et al., 1997, Rodan et al., 2002, Martin et al., 1999, Kahsai et al., 2010, Kahsai and Winther, 2011)
Alleles and Phenotypes
Causes alleles	Scer\GAL4^c584 (Manseau et al., 1997, Rodan et al., 2002, Martin et al., 1999, Kahsai et al., 2010, Kahsai and Winther, 2011)

Lethality References
Sterility References
Phenotype Manifest In

Detailed Description
Statement Reference
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS) Stage Tissue/Position (including subcellular localization) Reference wandering third instar larval stage wing disc \| restricted (Manseau et al., 1997) ventral nerve cord \| posterior (Manseau et al., 1997) haltere disc \| restricted (Manseau et al., 1997) adult stage large field neuron \| vicinity of (Martin et al., 1999) Comment:expression is tangential to large field fan-shaped body (Kahsai et al., 2010)
Additional Information
Statement Reference Expression of Scer\GAL4[c584] is seen in a cluster of dorsolateral neurons posterior to the fan shaped body in each hemisphere. (Kahsai et al., 2010) Adult expression is observed in a cluster of five or six tangential large field neurons with cell bodies located in the dorso-caudal cellular cortex lateral to the calyx of the mushroom body. The axons of these neurons arborize in the rostro-dorsal protocerebrum, near the tip of the α'-lobe of the mushroom body, and dorsally in the fan-shaped body. Additional expression is observed in the antennal nerve, in a few neurons in the antennal lobe, and faintly in the anterior part of the ellipsoid body, as well as in three or four neurons in the pars intercerbralis projecting to the anterior median bundle. (Martin et al., 1999) In third instar larva, expressed in discrete groups of cells in the posterior segment of the ventral ganglion; expressed in a small number of patches in the wing disc and the haltere disc. (Manseau et al., 1997)

Marker for	large field neuron \| tangential (Martin et al., 1999)
Reflects expression of
Reporter construct used in assay	Mmus\Cd8a^{Scer\UAS.T:Avic\GFP} (Kahsai et al., 2010) shi^1.Scer\UAS (Kahsai et al., 2010)
External Images
FlyView (LinkOut)
Data on Genetic Line
Line ID
Origin as a multiple insertion line
Progenitor(s) within the Genome

Related Aberration or Balancer
Aberration
Balancer
Stocks ( 1 )
Bloomington	30842 w^*; P{GawB}c584
Linkouts
Synonyms & Secondary IDs
Reported As
Symbol Synonym	c584 (Rodan et al., 2002, Manseau et al., 1997, Kahsai et al., 2010, Kahsai and Winther, 2011) P[GAL4]C584 (Martin et al., 1999) P{GawB}c584 (Manseau et al., 1997, FlyBase, 1992-, Cook, 2010.7.28) P^GAL4 C584 (Martin et al., 1999)
Secondary FlyBase IDs

References ( 8 )
Research paper	Kahsai and Winther, 2011, J. Comp. Neurol. 519(2): 290--315 Chemical neuroanatomy of the Drosophila central complex: distribution of multiple neuropeptides in relation to neurotransmitters. [FBrf0212649] Kahsai et al., 2010, J. Exp. Biol. 213(13): 2256--2265 Neuropeptides in the Drosophila central complex in modulation of locomotor behavior. [FBrf0211022] Rodan et al., 2002, J. Neurosci. 22(21): 9490--9501 Functional dissection of neuroanatomical loci regulating ethanol sensitivity in Drosophila. [FBrf0152149] Martin et al., 1999, J. Comp. Physiol. A, Sens. Neural. Behav. Physiol. 185(3): 277--288 Central complex substructures are required for the maintenance of locomotor activity in Drosophila melanogaster. [FBrf0111965] Manseau et al., 1997, Dev. Dyn. 209(3): 310--322 GAL4 enhancer traps expressed in the embryo, larval brain, imaginal discs, and ovary of Drosophila. [FBrf0095642] Brand and Perrimon, 1993, Development 118(2): 401--415 Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. [FBrf0064375]
Personal communication to FlyBase	Cook, 2010.7.28, Mapping P{GawB} insertions. Mapping P{GawB} insertions. [FBrf0211367]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]