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| Term | antibody-dependent cellular cytotoxicity | ID (Ontology) | GO:0001788 (Gene Ontology) |
| Definition | Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.[ ISBN:0781735149 PubMed:11677095 PubMed:9581795 ] | ||
| Also Known As | "ADCC" ; "antibody dependent cell death" ; "antibody dependent cell killing" (for all, see Synonyms field below) | ||
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cell killing |__leukocyte mediated cytotoxicity__ leukocyte mediated immunity | |__leukocyte mediated cytotoxicity__| type II hypersensitivity | |__type IIa hypersensitivity________| antibody-dependent cellular cytotoxicity |__regulation of antibody-dependent cellular cytotoxicity |__negative regulation of antibody-dependent cellular cytotoxicity |__positive regulation of antibody-dependent cellular cytotoxicity |
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type IIa hypersensitivity leukocyte mediated cytotoxicity |
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External Crossreferences & Linkouts
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Wikipedia:Antibody-dependent_cell-mediated_cytotoxicity Wikipedia:Antibody-dependent_cellular_cytotoxicity |
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