FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term type IIa hypersensitivity ID (Ontology) GO:0001794 (Gene Ontology)
Definition An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.[ ISBN:0781735149 ]
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myeloid leukocyte mediated immunity______
hypersensitivity_________________________|
immunoglobulin mediated immune response__|
                                         type II hypersensitivity
                                          |__type IIa hypersensitivity
                                              |__antibody-dependent cellular cytotoxicity
                                              |   |__regulation of antibody-dependent cellular cytotoxicity(+)
                                              |__regulation of type IIa hypersensitivity
                                                  |__negative regulation of type IIa hypersensitivity(+)
                                                  |__positive regulation of type IIa hypersensitivity(+)
                                                  |__regulation of antibody-dependent cellular cytotoxicity(+)
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