FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term cytoskeleton ID (Ontology) GO:0005856 (Gene Ontology)
Definition A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.[ PubMed:16959967 PubMed:27419875 ]
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Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       7
Genes (FBgn)  GO_CELLULAR_COMPONENT      43
Genes (FBgn)  GO_MOLECULAR_FUNCTION       1
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN       4
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 cytoskeleton (all annotations which use CV term, excluding "NOT" statements)       7     43      4
     cytoskeleton | embryonic stage       1       --       --
     cytoskeleton | embryonic stage | germline clone       2       --       --
     cytoskeleton | germline clone       2       --       --
     cytoskeleton | larval stage       2       --       1
     cytoskeleton | oogenesis       3       --       3
     cytoskeleton | P-stage       3       --       2
     cytoskeleton | somatic clone       1       --       --
     is_active_in | cytoskeleton       --      26       --
     located_in | cytoskeleton       --      18       --
Spanning Tree (Parents/Children)
Only view relationship:
membraneless organelle___
intracellular organelle__|
                         intracellular membraneless organelle
                          |__cytoskeleton  1546 rec.
                              |__actin cytoskeleton 405 rec.
                              |   |__actin body
                              |   |__actin filament(+) 179 rec.
                              |   |__actin filament bundle(+) 35 rec.
                              |   |__actin wave
                              |   |__actomyosin(+) 25 rec.
                              |   |__Arp2/3 protein complex 11 rec.
                              |   |__cortical actin cytoskeleton(+) 46 rec.
                              |   |__dynactin complex(+) 12 rec.
                              |   |__F-actin capping protein complex(+) 4 rec.
                              |   |__mating projection actin fusion focus
                              |   |__myosin complex(+) 29 rec.
                              |   |__podosome(+) 1 rec.
                              |   |__postsynaptic actin cytoskeleton(+)
                              |   |__presynaptic actin cytoskeleton
                              |   |__striated muscle thin filament(+) 42 rec.
                              |__axoneme 134 rec.
                              |   |__axonemal basal plate 1 rec.
                              |   |__axonemal central apparatus(+) 2 rec.
                              |   |__axonemal doublet microtubule(+) 6 rec.
                              |   |__axonemal dynein complex(+) 36 rec.
                              |   |__axonemal heterotrimeric kinesin-II complex
                              |   |__axonemal microtubule(+) 16 rec.
                              |   |__axonemal nexin link
                              |   |__distal portion of axoneme 1 rec.
                              |   |__outer dynein arm docking complex 2 rec.
                              |   |__proximal portion of axoneme
                              |   |__radial spoke(+) 2 rec.
                              |   |__satellite fibril
                              |__bilobe structure
                              |__ciliary microtubule quartet
                              |__ciliary rootlet 11 rec.
                              |__conoid
                              |__contractile vacuole pore
                              |__cortical cytoskeleton 67 rec.
                              |   |__cortical actin cytoskeleton(+) 46 rec.
                              |   |__cortical microtubule cytoskeleton(+) 4 rec.
                              |   |__cytoskeleton of presynaptic active zone(+) 13 rec.
                              |   |__eisosome filament
                              |__deep fiber
                              |__goblet cell theca
                              |__intermediate filament cytoskeleton 5 rec.
                              |   |__intermediate filament(+) 5 rec.
                              |   |__neurofilament cytoskeleton
                              |   |__postsynaptic intermediate filament cytoskeleton
                              |   |__presynaptic intermediate filament cytoskeleton
                              |__investment cone 93 rec.
                              |__median body
                              |__microtubule bundle
                              |   |__axon microtubule bundle
                              |   |__cytoplasmic microtubule bundle
                              |   |__dynamic microtubule bundle
                              |   |__static microtubule bundle
                              |__microtubule cytoskeleton 1019 rec.
                              |   |__cortical microtubule cytoskeleton(+) 4 rec.
                              |   |__manchette
                              |   |__microtubule(+) 338 rec.
                              |   |__microtubule associated complex(+) 146 rec.
                              |   |__microtubule organizing center(+) 398 rec.
                              |   |__post-anaphase microtubule array(+)
                              |   |__preprophase band
                              |   |__spindle(+) 397 rec.
                              |__perinuclear theca
                              |   |__cytoskeletal calyx
                              |__polymeric cytoskeletal fiber 505 rec.
                              |   |__actin filament(+) 179 rec.
                              |   |__intermediate filament(+) 5 rec.
                              |   |__microtubule(+) 338 rec.
                              |   |__outer dense fiber
                              |__postsynaptic cytoskeleton
                              |   |__cytoskeleton of dendritic spine(+)
                              |   |__postsynaptic actin cytoskeleton(+)
                              |   |__postsynaptic intermediate filament cytoskeleton
                              |   |__postsynaptic septin cytoskeleton
                              |   |__postsynaptic spectrin-associated cytoskeleton
                              |__presynaptic cytoskeleton 14 rec.
                              |   |__cytoskeleton of presynaptic active zone(+) 13 rec.
                              |   |__presynaptic actin cytoskeleton
                              |   |__presynaptic intermediate filament cytoskeleton
                              |__septin cap
                              |   |__germ tube septin cap
                              |   |__hyphal septin cap
                              |__septin collar
                              |   |__cellular bud neck septin collar
                              |   |__hyphae septin collar
                              |__septin cytoskeleton 10 rec.
                              |   |__cleavage apparatus septin structure(+)
                              |   |__postsynaptic septin cytoskeleton
                              |   |__septin band(+)
                              |   |__septin cap
                              |   |__septin collar
                              |   |__septin complex(+) 9 rec.
                              |   |__septin filament array
                              |   |__septin ring 5 rec.
                              |   |__split septin rings
                              |__septin filament array
                              |   |__chlamydospore septin filament array
                              |   |__prospore septin filament array
                              |__septin ring 5 rec.
                              |   |__cellular bud neck septin ring(+)
                              |   |__germ tube septin ring
                              |   |__hyphal septin ring
                              |   |__mating projection septin ring
                              |   |__medial cortex septin ring
                              |   |__prospore septin ring
                              |   |__pseudohyphal septin ring
                              |__spectrin-associated cytoskeleton 1 rec.
                              |   |__postsynaptic spectrin-associated cytoskeleton
                              |__spindle matrix 3 rec.
                              |__split septin rings
                              |   |__cellular bud neck split septin rings
                              |__subpellicular network
                              |__tripartite attachment complex
                              |__tubulin complex
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Is a intracellular membraneless organelle
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Wikipedia:Cytoskeleton