FB2025_05 , released December 11, 2025
FB2025_05 , released December 11, 2025
CV Term Report
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General Information
Term insulin receptor signaling pathway ID (Ontology) GO:0008286 (Gene Ontology)
Definition The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
Also Known As "insulin receptor signalling pathway"
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      33
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 insulin receptor signaling pathway (all annotations which use CV term, excluding "NOT" statements)       2     33
     involved_in | insulin receptor signaling pathway       --      33
Spanning Tree (Parents/Children)
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enzyme-linked receptor protein signaling pathway
 |__cell surface receptor protein tyrosine kinase signaling pathway__
response to insulin                                                  |
 |__cellular response to insulin stimulus____________________________|
cellular response to peptide hormone stimulus                        |
 |__cellular response to insulin stimulus____________________________|
                                                                     insulin receptor signaling pathway  89 rec.
                                                                      |__regulation of insulin receptor signaling pathway 56 rec.
                                                                          |__negative regulation of insulin receptor signaling pathway(+) 32 rec.
                                                                          |__positive regulation of insulin receptor signaling pathway(+) 23 rec.
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Is a cell surface receptor protein tyrosine kinase signaling pathway
Part of cellular response to insulin stimulus
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Synonyms
  • "daf-2 receptor signaling pathway" NARROW
    "insulin receptor signalling pathway" EXACT
Secondary IDs
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Reactome:R-HSA-74752 "Signaling by Insulin receptor"